Mark Swanson

Picture of Mark Swanson
Associate Professor, Otolaryngology
School of Medicine
B.A., Miami University, 2007, Chemistry
M.D., The Ohio State University, 2011
Phone: (714) 456-5753
Fax: (714) 456-5753
Email: mswanso2@hs.uci.edu
University of California, Irvine
UCIMC-ENT 333 City Blvd West, Suite 525 Orange
Mail Code: 5386
Irvine, CA 92697
Research Interests
Head and Neck Cancer, Cancer Prevention, Quality of care, Quality of Life
Awards and Honors
2008 Roadmap Training Program in Clinical Investigation - NIH
2009 Landachre Resarch Honors Society - Ohio State University
2010 AOA Medical Honor Society
2010 Outstanding Academic Merit Scholarship - Ohio State University
2010 Article of the Month Osteoarthritis and Cartilage Journal, Oxford, UK
2014 Prevention & Early Detection Community Service Grant - American Head and Neck Society
2017 Otolaryngology Fellow Teaching Award - University of Miami
2019 Mentor for Resident Research Award First Prize - Dr. Bertelsen - University of Southern California
2021 Physician Partner of the Year Nomination - Nurses Week, Keck Medical Center
2022 “Qualitative Interview on Patient Perceptions of Head and Neck Cancer Treatment” - Podium Presentation Awarded for Mentee - Swathi Balaji - Keck School of Medicine of USC
2022 Joseph Gordon-Levitt Award For Excellence in Academic Medicine - University of Southern California
2021-2022 Faculty Teaching Award - University of Southern California, Department
of Otolaryngology

2020 Top Doctor Los Angeles Magazine, Los Angeles, CA
2021 Top Doctor Los Angeles Magazine, Los Angeles, CA
2021 Top Doctor Pasadena Magazine, Pasadena, CA
2022 Top Doctor Los Angeles Magazine, Los Angeles, CA
2022 Top Doctor Pasadena Magazine, Pasadena, CA
2023 Top Doctor Los Angeles Magazine
2023 Top Doctor Pasadena Magazine
Short Biography
I am an Associate Professor in the Department of Otolaryngology Head & Neck Surgery at the University of California – Irvine. My research focuses on clinical outcomes, predictors, and quality of life measures for head and neck cancer patients. I have published research in improving post-operative recovery using ERAS, developing protocols for improved swallowing after treatment, evaluation of nodal metastasis as predictors for cancer recurrence, and seriocomic and insurance factors in access to care.

Through my outcomes research, I have had a specific focus on improved postoperative recovery, improving discharge to home, and minimizing chronic opiate use. This has been done through work involving multimodal analgesia to reduce opioid use, and predictors of pain based on extent and type of reconstruction used. I am expanding this research to see how opioid sparing pain protocols impact future chronic opiate prescription use.
Publications
1. Huang MY, Chen A, Quarshie C, Masson R, Barajas G, Kim G, DeClerck B, Swanson MS, In GK, Kokot N, Pickering TA, Hu JC. Influence of Anatomic Locations of T1b Melanomas and Patient Age on Outcomes. J Drugs Dermatol. 2024 May 1;23(5):306-310. PMID: 38709694.

2. Ayo-Ajibola O, Davis RJ, Lin ME, Vukkadala N, O'Dell K, Swanson MS, Johns MM 3rd, Shuman EA. TrachGPT: Appraisal of tracheostomy care recommendations from an artificial intelligent Chatbot. Laryngoscope Investig Otolaryngol. 2024 Jul 16;9(4):e1300. PMID: 39015552; PMCID: PMC11250132.

3. Nurimba M, Sheth M, Swanson M, Chambers T. The Impact of Race and the Affordable Care Act on Thyroid Carcinoma Outcomes: A National Cancer Database Study. Laryngoscope. 2024 Oct;134(10):4421-4430. Epub 2024 Jun 6. PMID: 38841865.

4. Hermann J, Atay S, Swanson M. A Painless Right Anterior Neck Mass. JAMA Otolaryngol Head Neck Surg. 2024 Feb 1;150(2):181-182. PMID: 38127334.

5. Davis RJ, Ayo-Ajibola O, Lin ME, Swanson MS, Chambers TN, Kwon DI, Kokot NC. Evaluation of Oropharyngeal Cancer Information from Revolutionary Artificial Intelligence Chatbot. Laryngoscope. 2024 May;134(5):2252-2257. PMID: 37983846.

6. Swanson MS, Gantz O, Zhou S, Fisher L, Kezirian E, Tan MH, Zhang Y, Chambers TN, Sinha UK, Kokot N. Comparison of Free Flap Outcomes at a University Hospital versus County Hospital Setting for Head and Neck Reconstruction. Int Arch Otorhinolaryngol. 2023 Apr 28;27(2):e183-e190. PMID: 37125366.

7. Bove I, Pangal DJ, Ruzevick JJ, Cheok S, Amar A, Mack W, Ference ED, Wrobel B, Swanson M, Hur K, Zada G. Anatomic Considerations Guiding Single Versus Multiportal Endoscopic Approaches for Resection of Juvenile Nasopharyngeal Angiofibroma: Cases Series With Graded Multicorridor Resections. Oper Neurosurg (Hagerstown). 2023 Aug 1;25(2):150-160. PMID: 37166983.

8. Castellanos CX, Paoletti M, Ulloa R, Kim C, Fong M, Xepoleas M, Sinha U, Kokot N, Swanson MS. Opioid Sparing Multimodal Analgesia for Transoral Robotic Surgery: Improved Analgesia and Narcotic Use Reduction. OTO Open. 2023 Mar 14;7(1):e17. PMID: 36998552.

9. Ziltzer RS, Millman NM, Serrano J, Swanson M, O'Dell K. Creation of an Open Bedside Tracheostomy Program at a Community Hospital With a Single Surgeon. OTO Open. 2023 Feb 17;7(1):e27. PMID: 36998547.

10. Tang L, West J, Lee E, Kharidia K, Hasday S, Chambers T, Kokot N, Swanson M, O'Dell K. Open Bedside Tracheostomy: Safe and Cost Saving but Underutilized Nationally. Otolaryngol Head Neck Surg. 2022 Apr 5:1945998221091905. PMID: 35380905.

11. Castellanos CX, Ulloa R, Kim C, Tang L, Swanson M, Kokot N. Enhanced recovery after surgery: a narrative review on perioperative pain levels and opiate use following free flap reconstruction in patients with head and neck cancer. J Oral Maxillofac Anesth 2022;1:14.

12. Wu FM, Yu AJ, Choi JS, Swanson MS, Chambers TN, Kokot NC, Sinha UK. Human papillomavirus detection in oral rinses and history of tonsillectomy in U.S. adults. Am J Otolaryngol. 2022 Nov-Dec;43(6):103558. Epub 2022 Aug 3. PMID: 36029622.

13. Pangal DJ, Cote DJ, Ruzevick J, Yarovinsky B, Kugener G, Wrobel B, Ference EH, Swanson M, Hung AJ, Donoho DA, Giannotta S, Zada G. Robotic and robot-assisted skull base neurosurgery: systematic review of current applications and future directions. Neurosurg Focus. 52(1):E15, 2022 Jan. PMID: 34973668.

14. Inouye D, Zhou S, Clark B, Swanson M, Chambers T. Two Cases of Impaired Wound Healing Among Patients With Major Head and Neck Free-Flap Reconstruction in the Setting of COVID-19 Infection. Cureus. 2021 Dec 1;13(12):e20088. PMID: 34993036.

15. West JD, Kim ME, Lapalma DM, Vergara-Lluri M, Conti P, Chambers TN, Swanson MS. 18FDG-PET/CT Specificity for the Detection of Lymphoma Recurrence in the Tonsils. OTO Open. 2021 Nov 15;5(4):2473974X211059081. PMID: 34805720.

16. Paik CB, Kim C, Nurimba M, Castellanos CX, Martinez E, Kokot N, Kwon D, Swanson MS, Sinha UK. Outcomes of Microvascular Reconstruction for Head and Neck Cancer in a COVID-19 Hot Spot. Ann Clin Otolaryngol. 6(1): 1050, 2021.

17. Kim C, Martinez E, Kulich M, Swanson MS. Surgeon practice patterns in transoral robotic surgery for HPV-related oropharyngeal cancer. Oral Oncol. 121:105460, 2021. PMID: 34298289.

18. Liu DH, Yu AJ, Ding L, Swanson MS. Association Between Insurance Type and Outcomes of Reconstructive Head and Neck Cancer Surgery. Laryngoscope. 2022 Oct;132(10):1946-1952. doi: 10.1002/lary.29966. PMID: 34846071.

19. Liu D, Pickering T, Kokot N, Crookes P, Sinha UK, Swanson MS. Outcomes of Combined Antegrade-Retrograde Dilations for Radiation-Induced Esophageal Strictures in Head and Neck Cancer Patients. Dysphagia. 36(6):1040-1047, 2021. PMID: 33386998.

20. In GK, Vaidya P, Filkins A, Hermel DJ, King KG, Ragab O, Tseng WW, Swanson M, Kokot N, Lang JE, Menendez L, DeClerck B, Kim G, Hu JC, Terando A, Jadvar H, Ricker C, Miller KA, Peng DH, Wysong A. PD-1 inhibition therapy for advanced cutaneous squamous cell carcinoma: a retrospective analysis from the University of Southern California. J Cancer Res Clin Oncol. 147(6):1803-1811, 2021. PMID: 33210210.

21. Clark BS, Swanson M, Widjaja W, Cameron B, Yu V, Ershova K, Wu FM, Vanstrum EB, Ulloa R, Heng A, Nurimba M, Kokot N, Kochhar A, Sinha UK, Kim MP, Dickerson S. ERAS for Head and Neck Tissue Transfer Reduces Opioid Usage, Peak Pain Scores, and Blood Utilization. Laryngoscope. 131(3):E792-E799, 2021. PMID: 32516508.

22. Nurimba M, Hines W, Sinha U, Mathew A, Kokot N, Swanson M. Evaluation of lymph node ratio and lymph node yield as prognosticators of locoregional recurrence in p16-associated oropharyngeal squamous cell carcinoma. Head Neck. 42(10):2811-2820, 2020. PMID: 32542889.

23. Itamura K, Kokot N, Sinha U, Swanson M. Association of insurance type with time course of care in head and neck cancer management. Laryngoscope. 130(11):E587-E592, 2020. PMID: 31756005.

24. Choi JS, Tang L, Yu AJ, Swanson MS, Chambers TN, Kokot NC, Sinha UK. Prevalence of oral human papillomavirus infections by race in the United States: An association with sexual behavior. Oral Dis. 26(5):930-940, 2020. PMID: 32011771.

25. Bertelsen C, Hur K, Nurimba M, Choi J, Acevedo JR, Jackanich A, Sinha UK, Kochhar A, Kokot N, Swanson M. Enhanced Recovery After Surgery-Based Perioperative Protocol for Head and Neck Free Flap Reconstruction. OTO Open. 4(2):2473974X20931037, 2020. PMID: 32537554.

26. Yu AJ, Choi JS, Swanson MS, Kokot NC, Brown TN, Yan G, Sinha UK. Association of Race/Ethnicity, Stage, and Survival in Oral Cavity Squamous Cell Carcinoma: A SEER Study. OTO Open. 3(4):2473974X19891126, 2019. PMID: 31840132.

27. Sinha UK, Swanson MS, Villegas BC, Ouyoung LM, Kokot N. Outcomes of Self-Esophageal Dilation for Head and Neck Cancer Patients. Am J Speech Lang Pathol. 28(3):1060-1066, 2019. PMID: 31112391.

28. Bertelsen C, King KG, Swanson M, Duddalwar V, Pepper JP. Contrast-enhanced ultrasound with perflubutane for sentinel lymph node mapping in cutaneous melanoma: A pilot study. Laryngoscope. 129(5):1117-1122, 2019. PMID: 30284307.

29. Ouyoung LM, Swanson MS, Villegas BC, Damodar D, Kokot N, Sinha UK. ABCLOVE: Voice therapy outcomes for patients with head and neck cancer. Head Neck. 38 Suppl 1:E1810-3, 2016. PMID: 26689974.

30. Swanson MS, Low G, Sinha UK, Kokot N. Transoral surgery vs intensity-modulated radiotherapy for early supraglottic cancer: a systematic review. Curr Opin Otolaryngol Head Neck Surg. 25(2):133-141, 2017. PMID: 28106658.

31. Swanson MS, Kokot N, Sinha UK. The Role of HPV in Head and Neck Cancer Stem Cell Formation and Tumorigenesis. Cancers (Basel). 8(2):24, 2016. PMID: 26907349.

32. Swanson MS, Sinha UK. Rationale for combined blockade of PD-1 and CTLA-4 in advanced head and neck squamous cell cancer—review of current data. Oral Oncol. 51(1):12-5, 2015. PMID: 25459157.

33. Swanson MS, Hudson RL, Bhandari N, Sinha UK, Maceri DR, Kokot N. Use of Octreotide for the Management of Chyle Fistula Following Neck Dissection. JAMA Otolaryngol Head Neck Surg. 141(8):723-7, 2015. PMID: 26135979.

34. Radhakrishnan V, Swanson MS, Sinha U. Monoclonal Antibodies as Treatment Modalities in Head and Neck Cancers. AIMS Medical Science. 2. 347-359. 10.3934/medsci.2015.4.347, 2015.

35. Swanson MS, Sinha UK. Diagnosis and management of merkel cell carcinoma of the head and neck: current trends and controversies. Cancers (Basel). 27;6(3):1256-66, 2014. PMID: 24978433.

36. Swanson MS, Prescott JW, Best TM, Powell K, Jackson RD, Haq F, Gurcan MN. Semi-automated segmentation to assess the lateral meniscus in normal and osteoarthritic knees. Osteoarthritis Cartilage. 18(3):344-53, 2010. PMID: 19857510.

37. Prescott JW, Best TM, Swanson MS, Haq F, Jackson RD, Gurcan MN. Anatomically anchored template-based level set segmentation: application to quadriceps muscles in MR images from the Osteoarthritis Initiative. J Digit Imaging. 24(1):28-43, 2011. PMID: 20049623.

38. Prescott J, Swanson M, Hoang K, Pennell M, Haq F, Best T, Jackson R, Gurcan M. Relationship between meniscus volume and cartilage morphology in MR images of osteoarthritis patients. Osteoarthritis and Cartilage. 17. 10.1016/S1063-4584(09)60054-6, 2009.

39. Prescott J, Swanson M, Hoang K, Pennell M, Haq F, Best T, Jackson R, Gurcan M. Template-based level set segmentation using anatomical information: Application to Quadriceps Muscles in MR Images from the Osteoarthritis Initiative. 24th International Symposium on Computer and Information Sciences. 1(1): 24-29, 2009.

40. Prescott JW, Pennell M, Best TM, Swanson MS, Haq F, Jackson R, Gurcan MN. An automated method to segment the femur for osteoarthritis research. Annu Int Conf IEEE Eng Med Biol Soc. 2009:6364-7, 2009. PMID: 19964163.

41. Prescott JW, Priddy M, Best TM, Pennell M, Swanson MS, Haq F, Jackson RD, Gurcan MN. An automated method to detect interstitial adipose tissue in thigh muscles for patients with osteoarthritis. Annu Int Conf IEEE Eng Med Biol Soc. 6360-3, 2009. PMID: 19964162.

42. Haq F, Gurcan M, Powell K, Jackson R, Prescott J, Swanson M, Best T. Knee strength predicts loss of function and decline in physical activity in participants with osteoarthritis: A 2yr follow-up of the oai study. Osteoarthritis And Cartilage. 027 17. 10.1016/s1063-4584(09)60050-9, 2009.
BOOKS & CHAPTERS

1. Kokot N, Swanson MS, Weinstein GS. Management of the N3 Neck. Medscape Reference. Available at: http://emedicine.medscape.com/article/850589-overview. 2014

2. Liu, C, Swanson MS, Kokot N. Robotic Surgery: Clinical Perceptions, Approaches and Challenges. Chapter 16: Transoral Robotic Surgery: Treatment of Head and Neck Disease. Lazar, John F. Nova Science Publishers. p391-407, 2018.
Grants
Grant No. (PI) - GR1056363 (Mark Swanson MD) Dates of Award: 2021-2022 Agency: Hemostasis LLC Percent Effort: 15% Title: ACCEL® Absorbable Hemostat Powder Investigational Device Exemption (IDE) Randomized Clinical Trial Description: Randomized clinical trial for a hemostasis product compared to gelfoam in soft tissue head and neck surgery. Role: Principle Investigator Total Direct Costs $200,000.00
Grant No. (PI) – Trial 7H-22-2(Mark Swanson MD) Dates of Award: 2023 Agency: Norris Medical Center Percent Effort: 15% Title: A Phase II Open Label, Single Arm Study to Evaluate the Efficacy of Pembrolizumab for Leukoplakia Description: A clinical trial for effectiveness of pembrolizumab for oral leukoplakia with at least moderate dysplasia Role: Principle Investigator
Grant No. (PI) – NCT06227585 (Mark Swanson MD) Dates of Award: 2024 Agency: Alume Percent Effort: 15% Title: Feasibility Study - Reveal FGS475 System for Bevonescein-Assisted Intra Operative Visualization of Nerves in Head and Neck Surgery Description: To characterize the feasibility of using the REVEALTM 475 by obtaining surgeon perspective on 1. Illumination and 2. Ease of use Role: Principle Investigator
Professional Societies
American Head and Neck Society (AHNS)
The Triological Society
Last updated
09/19/2025