Maria Gnarra Buethe

Picture of Maria Gnarra Buethe
Assistant Professor, Dermatology
School of Medicine
Director of Pediatric and Adolescent Dermatology, Dermatology
School of Medicine
M.D., Ph.D., Università Cattolica del Sacro Cuore, Rome, Italy
Pediatric Internship, SUNY Downstate Health Science University, Brooklyn, NY
Dermatology Residency, SUNY Downstate Health Science University, Brooklyn, NY
Pediatric Dermatology Fellowship, Rady Children’s Hospital, University of California, San Diego, CA
University of California, Irvine
118 Medical Surge 1
Irvine, CA 92697
Research Interests
Vascular Anomalies, Genodermatosis/Rare skin disease, Complex Pediatric Dermatology
Awards and Honors
1. Erasmus Placement Scholarship. European Union. Three-month scholarship to conduct clinical training at European Institution. Imperial College of London, UK. 2009.
2. International Thesis Scholarship. European Union. Three-month research scholarship to conduct thesis projects at European Institutions; University College of London, UK. 2011.
3. Graduate with High Distinction. University Cattolica Sacro Cuore, Roma, Italy. 2012.
4. Doctor J Fellowship. National Institute of Social Welfare, Italy. Merit scholarship with full PhD salary and tuition coverage. 2012.
5. Ph.D. Student Research Initiative Award. Genzyme. 1st Prize among 5 finalists/internationally selected abstract. 2012.
6. Summer School: Transferable Skills for Research Career Scholarship. Università Cattolica del Sacro Cuore, Milan, Italy. Five scholarships awarded, on a competitive base to attend leadership course in science entrepreneurship, Milan, Italy. 2013.
7. ESDR Educational Grant. European Society of Dermatology Research (ESDR) Research Career Scholarship. One PhD student from each European country is selected, on a competitive base, to attend the Summer Research Workshop: Mouse model in skin research, Cologne, Germany. 2013.
8. Outstanding Poster Award. Italian Society of Dermatology and Venereology (SIDEMAST). 1st Prize among 10 finalists/125 nationally selected abstract. 2013.
9. Best Scientific Presentation Award. UCSC, Rome, Italy/Amicus Therapeutics. Awarded four best original scientific studies in personalized therapy. National Competition. 2014.
10. O. Enjolras Award for Promising Investigators in the Field of Vascular Anomalies. International Society for the Study of Vascular Anomalies (ISSVA). One clinician/researcher selected internationally based on achievements in the field of vascular anomalies. Award presented at the 20th ISSVA congress, Melbourne, Australia. 2014.
11. LE&RN Travel Award. Lymphatic Education & Research Network (LE&RN). Two PhD students selected on competitive base to attend the NIH Lymphatic Symposium, Bethesda, MD. 2015.
12. Doctor Europeaus. University Cattolica Sacro Cuore, Roma, Italy. Additional Doctorate title awarded for performing additional graduate research in leading European institutions, Great Ormond Street Hospital, London, UK. 2016.
13. Young Italy Award; Category: Medicine. American Studies Center, Rome, Italy. Ten professionals (one for each category) under 35-year-old awarded based on achievements in their field. 2016.
14. ESDR Munich Travel Grant. European Society of Dermatology Research (ESDR). One clinician/researcher is selected, on a competitive base, to attend and present at the 46th ESDR meeting in Munich, Germany. 2016.
15. VBF Travel Award. Vascular Birthmark Foundation (VBF). One clinician/researcher working in the vascular anomaly field selected to attend and present at the Annual VBF Conference & Clinic, NY. 2016.
16. ESDR/SID Collegiality Award. European Society for Dermatology Research (ESDR)/ Society of Investigative Dermatology (SID). One researcher in the dermatology field selected, on a competitive base. Award presented at the 76th Annual Society for Investigative Dermatology meeting, Portland. 2017.
17. PhD Research Award. National Institute of Social Welfare, Italy. National recognition of distinction for doctorate thesis. 2017.
18. S. Chimenti Award-Best Research Study in the Dermatology. Associazione Dermatologi Magna Grecia. 1st Prize among presented research studies. 2017.
19. AAP Legislative Conference Scholarship. American Academy of Pediatrics (AAP). Travel stipend for pediatric residents with proven leadership roles in healthcare policy to attend the Legislative Conference in Washington DC. 2020.
20. Case of the Year. Society for Pediatric Dermatology. Selected cases among submitted abstracts. 2021.
21. Resident Presentation Award. Dermatologic Society of Greater New York. Annual Stritzler Resident Competition. 2022.
22. Rising Derm Star Award. Pfizer. Twenty US dermatology residents and fellows awarded full travel scholarship to attend the 2023 Winter Clinical Dermatology Conference in Hawaii, HI. 2023.
23. Resident Night. Dermatologic Society of Greater New York (DSGNY). One resident from each ACGME residency program in New York State selected to present their research. 2023.
24. Resident Scholarship. Medscape. Travel Grant to attend Pigmentary Disorders Exchange Symposium, Chicago, IL. 2023.
25. Resident Scholarship. Medscape. Travel Grant to attend Women's & Pediatric Dermatology Seminar, Baltimore, MA. 2023.
26. Resident Award. 2nd Annual Dermatology Innovation Symposium, Anaheim, CA. Top 3 abstract selected to present at the 2nd Annual Dermatology Innovation Symposium, Anaheim, CA. 2023.
27. Resident Travel Award. American Contact Dermatitis Society. 2023.
28. Rising Derm Star & Meeting Commendation. Pfizer. Twenty US dermatology residents and fellows awarded full travel scholarship to attend the 2024 Winter Clinical Dermatology Conference in Honolulu, HI. 2024.
29. Resident of Distinction Award. DermMentors, Beiersdorf. Top five research projects selected for Podium Presentation at 2024 Maui Derm, Maui, Hi. 2024.
30. Case of the Year. Society for Pediatric Dermatology. Selected cases among submitted abstracts for podium presentation. 2024.
31. Resident Forum. CalDerm. Selected cases among submitted abstracts for Podium Presentation at NorCal conference. 2024.
32. Resident Forum. CalDerm. Selected cases among submitted abstracts for Podium Presentation at CalDerm 2024 Fall Symposium. 2024.
Publications
1. Zaffanello M, Gnarra M, Buonsenso D, Cataldi L, Zaffanello M. Le infezioni delle vie urinary del neonato. Rivista di Infettivologia Neonatale 2010; anno III, numero 2: 19-23. Rivista di Infettivologia Neonatale. 2010, Jan; III(2): 19-23.
2. Zampetti A, Gnarra M, Linder D. Digiuseppe MD, Carrino N, Feliciani C. Psoriatic Pseudobalanitis Circinata as a Post-Viral Koebner Phenomenon. Case Rep Dermatology. 2010, Nov; 2(3): 183–188. Cited in PubMed; PMID: 21113343.
3. Cataldi L, Zaffanello M, Gnarra M, Fanos V. Urinary tract infection in the newborn and the infant: state of the art. The Journal of Maternal-Fetal & Neonatal Medicine. 2010, Oct; 23(Sup 3): 90-93. Cited in PubMed; PMID: 20883144.
4. Zampetti A, Gnarra M, Linder D, Antuzzi D, Cataldi L, Tulli A, Feliciani C. Early-onset basal cell carcinoma in a case of Ivemark syndrome. European Journal of Dermatology. 2010, Nov; 20(6): 845-6. Cited in PubMed; PMID: 20959271.
5. Zampetti A, Orteu CH, Antuzzi D, Bongiorno MR, Manco S, Gnarra M, Morrone A, Cardinali G, Kovacs D, Aspite N, Linder D, Parini R, Feliciani C. Angiokeratoma: decision-making aid for the diagnosis of Fabry disease. British Journal of Dermatology. 2012, Apr; 166(4): 712-720. Cited in PubMed; PMID: 22452439.
6. Zampetti A, Gnarra M, Borsini W, Giurdanella F, Antuzzi D, Piras A, Smaldone C, Pieroni M, Cadeddu C, de Waure C, Feliciani C. Vascular endothelial growth factor (VEGF-a) in Fabry disease: association with cutaneous and systemic manifestations with vascular involvement. Cytokine. 2013, Mar; 61(3): 933-939. Cited in PubMed; PMID: 23332617.
7. Murabit A, Gnarra M, Mohamed A. Reversed palmaris longus muscle: Anatomical variant - case report and literature review. Can Journal Plastic Surgery. 2013, Apr; 21(1): 55-56. Cited in PubMed; PMID: 24431941.
8. Murabit A, Gnarra M, O'Grady K, Morhart M. Olson JL. Functional outcome after the Hoffer procedure. Plastic Reconstrive Surgery. 2013, Jun; 131(6): 1300-6. Cited in PubMed; PMID: 23714791.
9. Zampetti A, Decinti MD, Gnarra M, Massi G, Feliciani C, Linder D. "Eczema-like" leishmaniasis in an HIV patient. European Journal of Dermatology. 2013, Jul; 23(4): 542-4. Cited in PubMed; PMID: 24004717.
10. Zampetti A, Giurdanella F, Manco S, Linder D, Gnarra M, Guerriero G, Feliciani C. Acquired epidermodysplasia verruciformis: a comprehensive review and a proposal for treatment. Dermatologic Surgery. 2013, Jul; 39(7): 974–980. Cited in PubMed; PMID: 23437916.
11. Gnarra M, Rotoli M, Fabrizi C, Pagliarello G, Feliciani C. Lipoatrophia semicircularis: a case report and review of the literature. Clinical Dermatology. 2013, Sep; 1(3): 146 - 148.
12. Zampetti A, Fania L, Antuzzi D, Giurdanella F, Gnarra M, Bertola F, Lualdi S, Filocamo M, Morrone A, Feliciani C. Mutation identification of Fabry disease in families with other lysosomal storage disorders. Clinical Genetics. 2013, Sep; 84(3): 281-5. Cited in PubMed; PMID: 23210910.
13. Gnarra M, Rotoli M, Giurdanella F, Fabrizi G, Feliciani C. Herpes Zoster in an immunocompetent child: a case-based review. Clinical Dermatology. 2013, Sep; 1(3): 153-155.
14. Giurdanella F, Fania L, Gnarra M, Toto. Di Rollo D, Sauder DN, Feliciani C. A possible role for CD8+ T lymphocytes in the cell-mediated pathogenesis of pemphigus vulgaris. Mediators of Inflammation. 2013, Nov; 2013(764290): 1-5. Cited in PubMed; PMID: 24347833.
15. Gnarra M, Saraceni P, Rossi A, Murabit A, Caradonna E, Fania L, Feliciani C. Challenging Diagnosis of Peripillous Sheaths. Pediatric Dermatology. 2014, Jul; 31(4): 112-3. Cited in PubMed; PMID: 24846654.
16. Gnarra M, Castriota, M. Rowland, S.P. Bonalumi G, Glieca, F., Feliciani, Claudio. (2014). A Case of Pyoderma Gangrenosum After Long Saphenous Vein Harvesting. EJVES Extra. 47. 10.1016/j.ejvsextra.2013.11.005.
17. Solman L. Murabit A. Gnarra M, Harper JI, Syed SB, Glover M. Propranolol for infantile haemangiomas: single centre experience of 250 cases and proposed therapeutic protocol. Archives of disease in childhood. 2014, Aug; 99(12): 1132–1136. Cited in PubMed; PMID: 25123404.
18. Concolino D, Degennaro R, Parini R. Fabry Delphi working group. Delphi consensus on the current clinical and therapeutic knowledge on Anderson-Fabry disease. European Journal of Internal Medicine. 2014, Oct; 25(8): 751-6. Cited in PubMed; PMID:25123424.
19. Tellkamp F, Benhadou F, Bremer J, Gnarra M, Knu¨ver J, Schaffenrath S, Vorhagen S. Transgenic mouse technology in skin biology: generation of knocking mice. The Journal of Investigative Dermatology. 2014, Dec; 134(12): 1-3. Cited in PubMed; PMID: 25381772.
20. Gnarra M, Solman L, Harper J, Syed S. Propranolol and prednisolone combination for the treatment of segmental haemangioma in PHACES syndrome. The British journal of dermatology. 2015, Jul; 173(1): 242-6. Cited in PubMed; PMID: 25639889.
21. van der Zeeuw F, Murabit A, Volcano J, Torensma, Hay N, Thorburn G, Morris P, Sommerlad B, Gnarra M, van der Horst C, Kangesu L. A Reliable Method to Measure Lip Height Using Photogrammetry in Unilateral Cleft Lip Patients. The Journal of craniofacial surgery. 2015, Sep; 26(6): 1865-70. Cited in PubMed. PMID: 26147027
22. Shawber CJ, Lin L, Gnarra M, Sauer MV, Papaioannou VE, Kitajewski JK, Douglas NC. Vascular Notch proteins and Notch signaling in the peri-implantation mouse uterus. Vascular cell. 2015, Dec; 7(9): 1-17. Cited in PubMed; PMID: 26629328.
23. Garcovich S,* Gnarra M,* Murabit A, Arena V, Sani I, Feliciani C. First report of hereditary Christ-Siemens-Touraine syndrome and non-segmental vitiligo association in a young adult: contraindication for vitiligo treatment. Journal of the European Academy of Dermatology and Venereology. 2016, Feb; 30(2): 346-8. Cited in PubMed; PMID: 25339629.
24. Gnarra M, Behr G, Kitajewski A, Wu JK, Anupindi SA, Shawber CJ, Zavras N, Schizas D, Salakos C. Economopoulos KP. History of the infantile hepatic hemangioma: From imaging to generating a differential diagnosis. World Journal of Clinical Pediatrics. 2016, Aug; 5(3): 273-80. Cited in PubMed; PMID: 27610342.
25. Simoncini C, Chico L, Concolino D, Sestito S, Fancellu L, Boadu W, Sechi GP, Feliciani C, Gnarra M, Zampetti A, Salviati A, Scarpelli M, Orsucci D, Bonuccelli U, Siciliano G, Mancuso M. Mitochondrial DNA haplogroups may influence Fabry disease phenotype. Neuroscience Lett. 2016, Aug; 629(1): 58-61. Cited in PubMed; PMID: 27365132.
26. Petruzziello C, Sinatti D, Gnarra M, Migneco A, Tesori V, Graziani C, Gasbarrini A, Franceschi F, Ojetti V. May Gender or Ethnicity Affect Delta Over Baseline Values Obtained by 13-C Urea Breath Test? Reviews on Recent Clinical Trials. 2017, Jan; 12(3): 187 -192. Cited in PubMed; PMID: 28814259.
27. Bassi A,* Gnarra M,* Shaw L, Rampling D, Syed S. Inflammatory linear verrucous epidermal nevus: an unusual manifestation. G Ital di Dermatol Venereol. 2017, Feb; 152(1): 72-73. Cited in PubMed; PMID: 26426377.
28. Ojetti V, Petruzziello C, Migneco A, Gnarra M, Gasbarrini A, Franceschi F. Effect of Lactobacillus reuteri (DSM 17938) on methane production in patients affected by functional constipation: a retrospective study. European Review for Medical and Pharmacological Sciences. 2017, Apr; 21(7): 1702-1708. Cited in PubMed; PMID: 28429333.
29. Gnarra M, De Simone C. Garcovich M, Garcovich S. Low-Dose Cyclosporine A in the Treatment of Severe Atopic Dermatitis Complicated by Chronic Hepatitis C Virus Infection. Pediatric Dermatology. 2017, May; 34(3): 374-376. Cited in PubMed; PMID: 28382768.
30. Gnarra M, Murabit A. (2017, September 04). Concomitant Unusual Presentation of an Arteriovenous Malformation in a Mother and Child. https://doi.org/10.1177/2513826X17728266,
31. van Geel N, Boniface K, Seneschal J, Jacquemin C, Speeckaert R, Wolkerstorfer A, Bekkenk M, Lommerts JE, Hamzavi I, Pandya A, Eleftheriadou V, Ezzedine K, Giannarelli D, Gnarra M, Sperduti I, Prinsen C, Harris J, Taieb A, Picardo M. Meeting report: Vitiligo Global Issues Consensus Conference Workshop "Outcome measurement instruments" and Vitiligo International Symposium, Rome, Nov 30-Dec 3rd. Pigment Cell Melanoma Research. 2017, Jul; 30(4): 436-443. Cited in PubMed; PMID: 28379638.
32. van Geel N, Wolkerstorfer A. Ezzedine K, Pandya AG, Bekkenk M. Grine L, Van Belle S. Lommerts JE, Hamzavi I, Harris JE, Eleftheriadou V, Esmat S, Kang HY, Kumarasinghe P, Lan CE, Parsad D, Raboobee N, Flora Xiang L, Suzuki T Prinsen CA, Taieb A Pica. Validation of a physician global assessment tool for vitiligo extent: Results of an international vitiligo expert meeting. Pigment Cell Melanoma Res. 2019, Sep; 32(5): 728-733. Cited in PubMed; PMID: 30945409.
33. Muley A, Kim Uh M, Salazar-De Simone G, Swaminathan B, James JM, Murtomaki A, Youn SW, McCarron JD, Kitajewski C, Gnarra Buethe M, Riitano G, Mukouyama YS, Kitajewski J, Shawber CJ. Unique functions for Notch4 in murine embryonic lymphangiogenesis. Angiogenesis. 2021 Oct 19. doi: 10.1007/s10456-021-09822-5. Epub ahead of print. PMID: 34665379.
34. Nguyen JK, Buethe M, Siegel DM. "Balloon Glove" Technique: An Easy Alternative to Pressure Dressing for Postoperative Hemostasis. Dermatol Surg. 2022 Jan 19. doi: 10.1097/DSS.0000000000003385. PMID: 35066553.
35. Buethe MG, Bayliss SJ, Shmuylovich L. Venous Malformations: A Journey Through Their Multifaceted Clinical Presentations. Dermatol Clin. 2022 Oct;40(4):435-443. doi: 10.1016/j.det.2022.06.001. Epub 2022 Sep 16. PMID: 36243430
36. Burshtein J, Buethe M.G., Ghias M, MD, Stein A.B, Glick S, Marmon S. Efficacy, Perception, and Utilization of Pediatric Teledermatology: A Systematic Review. JAADI- Volume 12, P3-11, September 2023. DOI:https://doi.org/10.1016/j.jdin.2023.03.005
37. Burshtein, J., Gnarra Buethe, M. (2024). Artificial Intelligence in Dermatology: A Review of Literature and Application to Pediatric Dermatology. SKIN The Journal of Cutaneous Medicine, 8(1), 1250–1257. https://doi.org/10.25251/skin.8.1.5
38. Buethe MG, Di Franco A, Uwakwe L, Glick SA. Treatment of Infantile Hemangiomas in Concomitant Tuberous Sclerosis Complex Should Prompt Evaluation for Cardiac Rhabdomyomas Prior to Initiation of Propranolol. Cutis. 2024 Jun;113(6):E14-E16. doi: 10.12788/cutis.1040. PMID: 39082988.
39. Buethe MG, Kellogg C, Seo YJ, Vuong C, Eichenfield LF. Topical Therapy for Atopic Dermatitis: What is New and the New Paradigm. Dermatol Clin. 2024 Oct;42(4):569-575. doi: 10.1016/j.det.2024.05.001. Epub 2024 Jun 15. PMID: 39278710.

Accepted
40. Chang H, Dykman M, Lara-Corrales I, Luu M, Wan J, Metry D, Buethe MG, et all. Highlights from the Field of Pediatric Dermatology Research from the 2023 PeDRA Annual Conference. Journal of Investigative Dermatology; JID-2024-0719.R1
Grants
2013. William Weston Research Award. Society for Pediatric Dermatology (SPD). Principal Investigator. $20,000
2013. E. Litta Foundation Fellowship. Fondation Genevoise de Bienfaisance Valeria Rossi di Montelera. Fellow/Mentee. CHF 60,000
2014. L’OREAL-UNESCO for Women in Science. L’OREAL-UNESCO Italy. Principal Investigator. €15,000
2014. La Roche-Posay Research Grant. LA ROCHE-POSAY European Foundation. Principal Investigator. € 25,000
2015. Dermatology Fellowship Award. IBSA Foundation. Fellow/Mentee. € 25,000
2015. SKINPACT-Excellence in Education Award. Galderma. Principal Investigator. $15,000
2016. Ermenegildo Zegna Founder’s Scholarship. Ermenegildo Zegna Group. Fellow/Mentee. € 30,000
2017. Dermatology Research Grant. European Academy of Dermatology and Venereology (EADV). Principal Investigator. € 30,000
2017. Foundation Blanceflor Scholarship. Foundation B. Boncompagni Ludovisi, née Bildt. Fellow/Mentee. SEK 170,000
2021. WDS Mentorship Award. Women Dermatologic Society (WDS). Fellow/Mentee. $2,000 (travel stipend)
2020. GME Wellness Fund. Graduate Medical Education (GME) SUNY Downstate. Principal Investigator. $2,000
2022. 2022 Equipment/Educational Materials Grant Patient Care Trust Fund-CIR. Co-Applicant. $90,925.00 for the purchase of Alexandrite/Nd:YAG laser + accessories, Candela GentleMax Pro
Professional Societies
Society of Pediatric Dermatology
CalDerm
San Francisco Dermatological Society
Pediatric Dermatology Research Alliance
Society of Investigative Dermatology
International Society for the Study of Vascular Anomaly
American Medical Association
Dermatology Foundation
American Academy of Dermatology
Group for Research and Assessment of Psoriasis and Psoriatic
American Society for Laser Medicine and Surgery
Society of Dermatology Hospitalists
International Society of Pediatric Dermatology
Last updated
11/18/2024