Professor | Associate Dean for Research
Sue & Bill Gross School of Nursing

Quality of Life, Health Outcomes, Biobehavioral, Neurocognition, Memory / Executive Function, Self-Care, Mental Health, Adolescent Transition, SDoH, Adolescents and Young Adults with Congenital Heart Disease, Quantitative / Qualitative

2023 Visiting Professor, Betty Irene Moore Stanford Heart Center
2022 STTI: International Nursing Researcher Hall of Fame Class of 2022
2018 Visiting Professor, Herma Heart Institute, Children's Hospital Wisconsin
2014 Harris Visiting Professor University of Illinois at Chicago
2013 Fellow in the American Academy of Nursing (FAAN)
2005 American Heart Association-Fellow in the Council of Cardiovascular Nursing (FAHA)

2024 Western Institute of Nursing, Anna M. Shannon Mentorship Award
2023 3rd Annual Florence Nightingale Invited Speaker – Association for European
Pediatric Cardiology (AEPC)
2022 Daisy Award – Teaching Excellence, UCLA School of Nursing
2020 American Heart Association Council on CVSN Excellence in Clinical Practice Award.
2019 Nancy Koster Memorial Lecturer at the Society of Pediatric Cardiovascular Nursing Annual Meeting.
2019 T. Garrett Rauch Nursing Lecture – 22nd Annual Update on Pediatric and Congenital Cardiovascular Disease.
2018 Association of Faculties of Pediatric Nurse Practitioners – Outstanding Researcher of the Year Award.
2018 UCLA School of Nursing Distinguished Alumni Award
2016 American Heart Association, Council of CVSN, Research Article of the Year Award
2015 European Society of Cardiology, London – Best Research Abstract
2014 National Association of Pediatric Nurse Practitioners – Lisa Milonovich Acute Care Pediatric Nurse Practitioner Scholar Award.
2013 Top 19 Medical and Nursing Professors in California by statestats.org
2013 Society of Pediatric Nursing – Excellence in Nursing Research Award
2013 National Association of Pediatric Nurse Practitioners – Los Angeles Chapter Nurse Practitioner of the Year Award
2012 UCLA Faculty Career Development Award
2007 Shirley Novel Nursing Alumni Award, Penn State University, School of Nursing
1999 American Association of Critical Care Nurses, Outstanding Advanced Practice Nurse Award
1994 Nursing Excellence Award, Lucile Packard Children’s Hospital at Stanford

Nancy Pike PhD, RN, CPNP-AC/PC, FAHA, FAAN, is Professor and Associate Dean for Research at the University of California, Irvine, Sue and Bill Gross School of Nursing. She continues to practice clinically as a nurse practitioner in pediatric cardiothoracic surgery at Children’s Hospital Los Angeles. She has received numerous accolades as a researcher, teacher, mentor, and clinician. Her biobehavioral and neuroimaging program of research has received several NIH/NINR/NIND-funded grants to study structural brain injury, cerebral blood flow, and its correlations to cognitive and psychosocial outcomes in adolescents and young adults with congenital heart disease (CHD), in particular, single ventricle heart disease (SVHD). She is the first to use an innovative computer-based cognitive intervention to improve working memory/attention in adolescents with SVHD. Furthermore, she validated a cognitive screening tool used in adolescents and adults in cardiology clinics across the country and is currently developing a disease-specific measure for self-care in CHD to use with transitioning to adulthood. Her findings have affected clinical practice to reduce or mitigate neurocognitive injury and standards of care for cognitive screening across the lifespan on a local national and international level. She is a fellow in the American Heart Association, the American Academy of Nursing, and the STTI International Nurse Researcher Hall of Fame. She is the current Chair of the American Heart Association Council of Cardiovascular and Stroke Nursing.

Gaynor JW, Stopp C, Wypij D, Andropoulos DB, Atallah J, Atz AM, Beca J, Donofrio MT, Duncan K, Ghanayem NS, Goldberg KS, Hövels-Gürich H, Ichida F, Jacobs JP, Justo R, Latal B, Li J, Mahle WT, McQuillen PS, Menon S, Pemberton V, Pike NA, Pizarro C, Shekerdemian LS, Synnes A, Williams I, Bellinger DC, and Newburger JW, International Cardiac Collaborative on Neurodevelopment (ICCON) Investigators. Neurodevelopmental Outcomes after Cardiac Surgery in Infancy: A Multi-Center Retrospective Analysis of Patient Factors Associated with Early Outcomes in 1,770 Subjects. Pediatrics, 2015; 135(5): 816-825.

Pike NA, Okuhara CA, Gross B, Wells W, Starnes VA. Fontan Protocol: Reducing Pleural Drainage, Hospital Length of Stay, Readmissions for Pleural Effusions and Hospital Costs. J Thorac Cardiovasc Surg. 2015; 150(3):481-487.

Ravishankar C, Gerstenberger E, Sleeper LA, Atz AM, Affolter J, Bradley TJ, Gaynor JW, Goldstein BH, Henderson H, Jacobs J, Lewis AB, Dunbar-Masterson C, Menon SC, Pemberton VL, Petit C, Pike NA, Pizarro C, Schumacher K, Williams IA, Newburger JW, for the Pediatric Heart Network. Factors affecting Fontan length of Stay: results from the Single Ventricle Reconstruction Trial. J Thorac Cardiovasc Surg. 2016; 151(3):669-675.

Pike NA, Woo MA, Poulsen MK, Evangelista W, Faire D, Halnon NJ, Lewis AB, Kumar R. Predictors of memory deficits in adolescents with and without congenital heart disease. Front Pediatr. 2016, 4:117. eCollection.

Pike NA, Poulsen MK, Woo MA. Validity of the Montreal Cognitive Assessment Screener in Adolescents and Young Adults with and without Congenital Heart Disease. Nursing Res. 2017, 66 (3):222-230.

Gaynor JW, Stopp C, Wypij D, Andropoulos DB, Atallah J, Atz AM, Beca J, Donofrio MT, Duncan K, Ghanayem NS, Goldberg KS, Hövels-Gürich H, Ichida F, Jacobs JP, Justo R, Latal B, Li J, Mahle WT, McQuillen PS, Menon S, Pemberton V, Pike NA, Pizarro C, Shekerdemian LS, Synnes A, Williams I, Bellinger DC, and Newburger JW. International Cardiac Collaborative on Neurodevelopment (ICCON) Investigators. Impact of Operation and Postoperative Factors on Neurodevelopmental Outcomes after Cardiac Operations. Ann Thorac Surg. 2016; 102(3): 843-849.

Mussatto KA, Trachtenberg F, Hollenbeck-Pringle D, Sood E, Sananes R, Pike NA, Linda Lambert L, Mahle WT, Goldberg D, Srey S, Goldberg C, Dunbar-Masterson C, Otto M, Marino BS, Bartle B, Williams I, Jacobs J, Zyblewski S, Pemberton V. Utilization of Early Intervention Services in Young Children with Hypoplastic Left Heart Syndrome. Cardiol Young. 2018; 28(1):126-133.

Pike NA, Gupta R, Roy B, Woo MA, Halnon NJ, Lewis AB, Kumar R. Brain Injury in Brain Abnormalities in Cognitive, Anxiety and Depression Regulatory Regions in Adolescents with Single Ventricle Heart Disease Compared to Controls. J Neurosci. Res. 2018; 96(6): 1104-1118.

Singh S, Kumar R, Roy B, Woo MA, Halnon NJ, Lewis AB, Pike N. Regional Gray Matter Changes in Adolescents with Single Ventricle Heart Disease. Neurosci Letters 2018; 665:156-162.

Singh S, Roy B, Pike N, Daniel E, Ehlert L, Lewis AB, Halnon NJ, Woo MA, Kumar R. Altered Brain Diffusion Tensor Imaging Indices in Adolescents with the Fontan Palliation. Neuroradiology 2019; 61(7):811-824.

Goldstone AB, Baiocchi M, Wypij D, Stopp C, Andropoulos DB, Atallah J, Atz AM, Beca J, Donofrio MT, Duncan K, Ghanayem NS, Goldberg CS, Hovels-Gurich H, Ichida F, Jacobs J, Justo R, Latal B, Li JS, Mahle WT, McQuillen PS, Menon SC, Pemberton VL, Pike NA, Pizarro C, Shekerdemian LS, Synnes A, Williams I, Bellinger DC, Newburger JW and Gaynor JW. International Cardiac Collaborative on Neurodevelopment (ICCON) Investigators. The Bayley-III Scale May Underestimate Neurodevelopmental Disability after Cardiac Surgery in Infants. European Journal for Cardio-Thoracic Surgery 2020; 57(1):63-71.

Rychik J, Atz A, Celermajer DS, Deal BJ, Gatzoulis MA, Gewillig MH, Hsia TY, Hus DT, Kovacs AH, McCrindle BW, Newburger JW, Pike NA, Rodefeld M, Rosenthal DN, Schumacher KR, Marino BS, Stout K, Veldtman G, Younoszai AK, Yves d’Udekem. Evaluation and Management of the Child and Adult with Fontan Circulation, American Heart Association Statement. Circulation 2019 July 1

Cabrera-Mino C, Roy B, Woo MA, Singh S, Moye S, Halnon NJ, Lewis AB, Kumar R, Pike NA. Reduced Mammillary Body Volumes and Memory Deficits in Single Ventricle Heart Disease. Pediatric Research 2020; 87(1):169-175.

Belson PJ, Eastwood JA, Brecht ML, Hays RD, Pike NA. A Review of Literature on Health-Related Quality of Life of Retinoblastoma Survivors. J Pediatr Oncol Nurs. 2020; 37(2):116-127.

Noorani S, Roy B, Sahib A, Halnon N, Woo MA, Lewis AB, Pike NA (Co-Senior Author), Kumar R. Caudate Nuclei Volume Changes and Cognitive and Mood Dysfunction in Adolescents with Single Ventricle Heart Disease. Journal of Neuroscience Research 2020 Jun 12 (online ahead of print).

Rudd N (Chair), Ghanayem N, Hill G, Lambert L, Mussatto K, Nieves J, Robinson S, Shirali G, Steltzer M, Uzark, Pike NA (Vice/Senior Chair). Interstage Home Monitoring of Infants with Single Ventricle Heart Disease: Education and Management. American Heart Association Scientific Statement. Journal of the American Heart Association 2020; 9(16):e014548.

Lambert L, Pike NA, Taylor-Piliae RE, Fink AM. Council on Cardiovascular and Stroke Nursing: Liaison Report from the Pediatric Cardiovascular Nursing Committee. Journal of Cardiovascular Nursing. 2020; 35(5):E15-17.

Kumar SR, Bainiwal J, Cleveland JD, Pike N, Wells WJ, Starnes VA. Impact of Prior Diaphragm Plication on Subsequent Stages of Single Ventricle Palliation. J Thorac Cardiovasc Surg. 2020, 160 (5):1291-1296.e.1

Peterson JK, Olshansky EF, Guo Y, Evangelista LS, Pike NA. Optimism Despite Profound Uncertainty: School and Social Relationships in Adolescents with Single Ventricle Heart Disease. Cardiology in the Young. 2021; 31: 252-259.

Pike NA Roy B, Moyer S, Cabrera-Mino C, Woo MA, Roy B, Halnon NJ, Lewis AB, Kumar R. Reduced Hippocampal Volumes are Associated with Memory Deficits in Adolescents with Single Ventricle Heart Disease. Brain and Behavior. 2021; 11(2): e01977.

Imperial-Perez F, Heilemann MS, Eastwood J, Doering L, Pike NA. Developing a Sense of Self-Reliance: Caregivers of Infants with Single Ventricle Heart Disease during the Interstage Period. Cardiology in the Young. 2022, 32(3):465-471.

Belson PJ, Eastwood JA, Brecht ML, Kim JW, Hays RD, Pike NA. Health-Related Quality of
Life in Adolescent and Young Adult Retinoblastoma Survivors. J Pediatr Hematol Oncol Nurs. 2022, 39(6):342-357.

Pike NA, Kinsler JJ, Peterson JK, Verzemnieks I, Lauridsen L, Love-Bibbero L, Ramos-Gomez R. Improved Oral Health Knowledge in a Primary Care Pediatric Nurse Practitioner Program. J Am Assoc Nurs Pract. 2022, 34(5):755-762.

Imperial-Perez F, Pike NA, Eastwood J, Doering L, Heilemann MS. Caregiving for Infants with Single Ventricle Heart Disease in the Interstage Period during COVID-19: A Continuous Process of Compromise. World J Pediatr Congenit Heart Surg. 2022, 13(4):443-450.

Nasr VG, Markham LW, DiNardo J, Faraoni D, Miller-Hance, WC, Gottlieb D, Clay M, Pike NA, Rotman C. Perioperative Considerations for Patients with Congenital Heart Disease Presenting for Non-Cardiac Procedures: A Scientific Statement from the American Heart Association. Circ Cardiovasc Qual Outcomes. 2023 16(1):e000113.

Pike NA, Love-Bibbero L, Kinsler JJ, Verzemnieks I, Ramos-Gomez F. Five-year follow-up of an interdisciplinary oral health educational program: clinical practice behaviors in working pediatric nurse practitioners. J Am Assoc Nurs Pract. 2022 Dec. 14

Gipson-McElroy K, & Pike NA. Development of an electronic medical record provider evaluation template for children with attention deficit/hyperactivity disorder. J Am Assoc Nurs Pract. 2023 35(1):5-11.

Ramos-Gomez F, Kinsler JJ, Love-Bibbero L, Garell CL, Pike NA. Mixed methods evaluation of an interprofessional education program for pediatric dental and medical care providers. J Dental Edu. 2023; 87(6):774-783

Belson PJ, Pike NA, Eastwood JA, Brecht ML, Berry JL, Hays RD. Vision-Related Quality of Life Compared to Generic Measures in Retinoblastoma Survivors. Quality of Life Research 2023, 32(4):1095-1105.

Hardy RY, Babu S, Jackson J, Andrews J, May S, Miller P, Timmins SK, Pike NA. Young Adults with Congenital Heart Disease Heading to College: Are College Health Centers and Providers Prepared? J Am Assoc Nurs Pract. 2023; 18:1-6.

Pike NA, Avedissian T, Halnon NJ, Lewis AL, Kumar R. Low Pre-Albumin Levels, and BMI are Associated with Cognitive Deficits in Adolescents Post-Fontan and Healthy Controls. Cardiol Young. 2023; 18:1-6.

Cabrera-Mino C, DeVon HA, Brecht ML, Aboulhosn J, Choi KR, Pike NA. Neurocognition in Adults with Congenital Heart Disease Post-Cardiac Surgery: A Systematic Review. Heart Lung. 2023; 64:62-73.

Westphaln KK, Imagawa KK, Smith L, Fan B, Pike NA. Risk Factors for Abuse in Children with Congenital Heart Disease Presenting to a Tertiary Care Hospital in Los Angeles. Congenital Heart Disease 2023; 18(6), 657-670.

Peterson J, Rudd N, Gelb, Setty S, Clarke S, Pieciak K, Kasparian N, Uveges M, Kazazian V, Pike NA. Trisomy 21 and Congenital Heart Disease: Impact on Health and Functional Outcomes. American Heart Association Scientific Statement (accepted, JAHA).

Kopelson K, de Peralta S, Pike NA. The One Minute Preceptor Improves Diagnostic Reasoning in a Primary Care Nurse Practitioner Residency Program" (accepted, J Am Assoc Nurs Pract.)

1F31NR020976-01 Diversity, Primary Sponsor (PI Cabrera-Mino) NIH / NINR, Sex Differences in Psychosocial and Neurocognitive Outcomes in Adults with Moderate to Complex Congenital Heart Disease

R21 AG081720, Co-Investigator (PI: Kumar R) Thiamine Intervention and Cognition in Older Adults Undergoing Coronary Artery Bypass Grafting- A Randomized Clinical Trial

1R21NS131850-01 (MPI Pike N & Kumar R) NIH / NINDS, Brain Metabolites, Antioxidants and Cerebral Blood Flow Deficits in Single Ventricle Heart Disease.

D88HP3903 Co-Investigator (PI Ramos-Gomez) US Department of Health and Human Services (HRSA) Community Access Reach Education in Pediatric Dentistry (CARE-PD)

1R21AG070269-01 Co-Investigator (Vacas & Kumar; MPI) NIH/NIA, Blood Brain Barrier Dysfunction and Perioperative Neurocognitive Disorders in Older Adults

UL1TR00188 NIH/National Center for Advancing Translational Sciences (Grant PI: Dubinett S.) Intramural Award (PI: Pike NA) Cognitive Intervention to Improve Working Memory in Adolescents with SVHD

R01NR016463 (MPI: Pike N & Kumar R) NIH / NINR, Cerebral Artery Integrity Linked to Brain Injury and Cognition in Congenital Heart Disease

1R01NR013930 (PI: Pike N) NIH / NINR, Memory and Brain Structures in Adolescents with Single Ventricle Heart Disease

1R01NR014669 Co-Investigator (MPI: Woo M & Kumar R), NIH / NINR, Blood-Brain Barrier Dysfunction and Brain Injury in Heart Failure

CDI-JFCD-07012018 William F. Friedman Endowed Fellowship, Primary Sponsor (PI: Patel, P) Assessment of Brain Pre-Frontal Cortex and Cognition in Adolescents with Single Ventricle Heart Disease

Western Institute of Nursing (WIN)

Pediatric Cardiac Intensive Care Society (PCICS)

American Nurses Association (ANA)

Society of Pediatric Cardiovascular Nurses (SPCN)

National Association of Pediatric Nurse Practitioners

International Society of Adult Congenital Heart Disease

American Heart Association (AHA)

Sigma Theta Tau International

Link to this profile
https://faculty.uci.edu/profile/?facultyId=7238

Last updated
04/28/2024