Jennifer Xu
Assistant Clinical Professor, Cardiology
School of Medicine
School of Medicine
B.S., University of Michigan
M.D., University of Michigan
Internal Medicine residency, UC Irvine
Cardiology fellowship, UC Irvine
M.D., University of Michigan
Internal Medicine residency, UC Irvine
Cardiology fellowship, UC Irvine
Email: jennifsx@uci.edu
University of California, Irvine
City Tower - Suite 400
Irvine, CA 92697
City Tower - Suite 400
Irvine, CA 92697
Research Interests
artificial intelligence, structural echocardiography, valvular heart disease
Websites
Awards and Honors
UCI Institute for Precision Health Pilot Grant, 2024-2025
UCI Department of Medicine Chair Research Award, 2024-2026
UCI Department of Medicine Chair Research Award, 2024-2026
Short Biography
My research focus is on the application of artificial intelligence in noninvasive cardiac imaging to aid in decision making for transcatheter interventions. Also with interest in cardiac critical care, athlete's heart, point-of-care ultrasound.
Publications
Presentations at Professional Meetings
Tran, N, Kim, B, Xu, J, Nobe, A. A silent predicament: Navigating sternal discomfort in a young athlete with genetic concerns. American Medical Society for Sports Medicine Annual Meeting, Kansas City, MO, 2025
Gurung P, Mikhail S, Matthew T, DiGrande K, Kim JK, Xu J. “Reevaluation of Tricuspid Regurgitation Severity: Evidence of Underdiagnosis in Routine Echocardiography.” American College of Cardiology Scientific Sessions, Chicago, 2025
Zuniga E, Jamali A, Xu J, Patel PM, Kim JK. “A Rare Right Ventricular Hamartoma.” American College of Cardiology Scientific Sessions, Chicago, 2025
Tang KS, Sidhu S, Jamali A, Xu J., Barseghian A, Huang A. A Rare and Interesting Case of Delayed Sheehan Syndrome and Post-Radiation Constrictive Pericarditis Presenting as New Decompensated Heart Failure with Pericardial Effusion. American College of Cardiology Scientific Sessions, Chicago, 2025
Xu, J., Kang J, Schilling J, Paganini-Hill A, Ericson M, Kim, J., Fisher, M. “Left Atrial Septal Pouch and Risk of Cryptogenic Stroke: A Systematic Review and Meta-Analysis.” International Stroke Conference, Los Angeles, 2025
Wu AT, Choi NH, Warren A, Shu G, Matthew T, Digrande K, Frangieh A, Kim JK, Xie X, Chang P, Xu J. “Automated detection of tricuspid regurgitation using multiple instance learning on Doppler echocardiograms.” Society for Imaging Informatics in Medicine Annual Meeting; Boston, 2024
Becerra, B., Xu, J., Rochon-Duck, Michael. “A Curious Case of a Congenital Channelopathy,” American College of Cardiology Care of the Athletic Heart course, Washington, D.C., 2024
Mathew, T., Patel, V., Goitia, J., Xu, J. “Hammering Out a Diagnosis: Near-Syncope Due to Occlusive Aortic Valvulopathy from a Cardiac Hamartoma,” American College of Cardiology Annual Meeting, Atlanta, GA, 2024.
Xu, J., Becerra B., Ghazarian A., Lyu Y., Schilling J.K., Nasr G., Zargarian E., Fan W., Wong N.D., and Kim J.K. “Devising a Scoring System With Echocardiography in Tamponade Assessment to Guide Pericardiocentesis (E-TAP).” American Society of Echocardiography Scientific Sessions; Seattle, WA, 2022.
Xu, J., Fan, W., Budoff, M.J., Heckbert, S.R., Amsterdam, E.D., Alonso, A., and Wong, N.D. “Intermittent Non-Habitual Coffee Consumption and Risk of Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.” American Heart Association Scientific Sessions; Chicago, IL, 2018.
Godbole, R., Xu, J., Shestakova, A., Youssef, F., Saatian, B. “Rare Variant of High-Grade B-Cell Lymphoma Presenting as a Pleural-Based Mass in an Immunocompetent Patient.” American Thoracic Society International Conference; San Diego, CA, 2018.
Xu, J., Tran, M., Baraghoush, A. “A tangled tale of thrombosis: managing anticoagulation in acute liver and kidney injury.” Society of General Internal Medicine Regional Meeting; Stanford, CA, 2018.
Hines, J., Xu, J. “Emphysematous pyelitis disguised as cholestasis and jaundice.” American College of Physicians Michigan Chapter Annual Scientific Meeting; Sterling Heights, MI, 2016.
Xu, J., Shuman, A.“Soothing and balmy, cure without disfigurement: Benjamin Bye, false promises, and head and neck cancer.” American Academy of Otolaryngology: Head and Neck Surgery Annual Meeting; Orlando, FL, 2014.
Gou, T., Xu, J., Blain-Moraes, S., Mashour, G. “Electroencephalographic power in subjects recovering from deep general anesthesia.” Summer Biomedical Research Program Symposium; Ann Arbor, MI, 2014.
Xu, J., Blain-Moraes, S., Mashour, G. “Directed phase lag index anticipates return of consciousness in subjects recovering from deep general anesthesia.” American Society of Anesthesiologists Annual Meeting; New Orleans, LA, 2014.
Liu, X.S., Chopp, M., Tang, T., Kassis, H., Xu, J., Hozeska-Solgot, A., Zhang, L., Zhang, R.L., and Zhang, Z.G. “The microRNA 17-92 cluster mediates sonic hedgehog-driven neurogenesis in ischemic neural progenitor cells.” International Stroke Conference; New Orleans, LA, 2012.
Publications
Xu, J., Kang J, Schilling J, Paganini-Hill A, Ericson M, Kim, J., Fisher, M. (2025). “Left Atrial Septal Pouch and Risk of Cryptogenic Stroke: A Systematic Review and Meta-Analysis.” Stroke Suppl_1
Xu, J., Haigney, M.C., Levine, B.D., & Dineen, E.H. (2024). “The Tactical Athlete: Definitions, Cardiovascular Assessment, and Management, and "Fit for Duty" Standards.” Cardiol Electrophys Clin, 16(1), 93-105. PMID: 36368814.
Xu, J., Kim, J., Fisher, M. (2024). “The enigma of the left atrial septal pouch.” Trends Cardiovasc Med. doi: 10.1016/j.tcm.2024.01.004.
Digrande, K., Xu, J., Shavelle, D., & Mendoza, F (2024). “Atrial tachycardia facilitating transcatheter edge-to-edge repair for severe functional mitral regurgitation.” JACC Case Reports. doi: 10.1016/j.jaccas.2024.102272
Digrande, K., Xu, J., Dineen, E., Lee, A. (2023). “Isolated double orifice mitral valve in a patient with autosomal dominant polycystic kidney disease.” Cardiovascular Imaging Case Reports. doi: 10.1016/j.case.2023.02.002
Xu, J., Haigney, M., Levine, B., Dineen, E. “The Tactical Athlete: Definitions, assessment, and management of symptoms.” Cardiology Clinics: Sports Cardiology 2022.
Xu, J., Becerra B., Ghazarian A., Lyu Y., Schilling J.K., Nasr G., Zargarian E., Fan W., Wong N.D., and Kim J.K. (2022). “Novel Risk Stratification Scoring System Based on Echocardiography in Tamponade Assessment to Guide Pericardiocentesis (E-TAP).” Journal of the American Society of Echocardiography 35(7).
Xu, J., Patel, P. “Aortic Coarctation.” Ferri’s Clinical Advisor 2022.
Xu, J., Fan, W., Budoff, M.J., Heckbert, S.R., Amsterdam, E.D., Alonso, A., and Wong, N.D. “Intermittent Non-Habitual Coffee Consumption and Risk of Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.” Journal of Atrial Fibrillation, 12(1), 1-6, 2019. PMID 31687073
Xu, J. “Commentary on ‘The Collective Lamentation of the Raggio Tomb.’” Academic Medicine, 94(7), 991, 2019.
Xu, J. “The body vanished: Sebald’s view of dissection in Rembrandt’s ‘The Anatomy Lesson of Dr. Nicolaes Tulp.’” Hektoen International: A Journal of Medical Humanities 6(4), 2014. Available from: http://hekint.org/2017/01/22/the-body-vanished-sebalds-view-of-dissection-in-rembrandts-the-anatomy-lesson-of-dr-nicolaes-tulp/
Xu, J., Shuman, A. “Soothing and balmy, cure without disfigurement”: Benjamin Bye, false promises, and head and neck cancer.” Otolaryngology – Head and Neck Surgery 152(4), 594-597, 2014. PMID 25338669
Xu, J. “I want to tea: an entering medical student’s perspective on geriatrics.” Journal of American Geriatrics Society, 61, 1411, 2013. PMID 23937489
Liu, X.S., Chopp, M., Wang, X.L., Tang, T., Hozeska-Solgot, A., Kassis, H., Zhang, L., Zhang, R.L., Chen, C., Xu, J., and Zhang, Z.G. “MicroRNA-17/92 cluster mediates the proliferation and survival of neural progenitor cells after stroke.” Journal of Biological Chemistry 288(18), 12478-12488, 2013. PMID 23511639
Tran, N, Kim, B, Xu, J, Nobe, A. A silent predicament: Navigating sternal discomfort in a young athlete with genetic concerns. American Medical Society for Sports Medicine Annual Meeting, Kansas City, MO, 2025
Gurung P, Mikhail S, Matthew T, DiGrande K, Kim JK, Xu J. “Reevaluation of Tricuspid Regurgitation Severity: Evidence of Underdiagnosis in Routine Echocardiography.” American College of Cardiology Scientific Sessions, Chicago, 2025
Zuniga E, Jamali A, Xu J, Patel PM, Kim JK. “A Rare Right Ventricular Hamartoma.” American College of Cardiology Scientific Sessions, Chicago, 2025
Tang KS, Sidhu S, Jamali A, Xu J., Barseghian A, Huang A. A Rare and Interesting Case of Delayed Sheehan Syndrome and Post-Radiation Constrictive Pericarditis Presenting as New Decompensated Heart Failure with Pericardial Effusion. American College of Cardiology Scientific Sessions, Chicago, 2025
Xu, J., Kang J, Schilling J, Paganini-Hill A, Ericson M, Kim, J., Fisher, M. “Left Atrial Septal Pouch and Risk of Cryptogenic Stroke: A Systematic Review and Meta-Analysis.” International Stroke Conference, Los Angeles, 2025
Wu AT, Choi NH, Warren A, Shu G, Matthew T, Digrande K, Frangieh A, Kim JK, Xie X, Chang P, Xu J. “Automated detection of tricuspid regurgitation using multiple instance learning on Doppler echocardiograms.” Society for Imaging Informatics in Medicine Annual Meeting; Boston, 2024
Becerra, B., Xu, J., Rochon-Duck, Michael. “A Curious Case of a Congenital Channelopathy,” American College of Cardiology Care of the Athletic Heart course, Washington, D.C., 2024
Mathew, T., Patel, V., Goitia, J., Xu, J. “Hammering Out a Diagnosis: Near-Syncope Due to Occlusive Aortic Valvulopathy from a Cardiac Hamartoma,” American College of Cardiology Annual Meeting, Atlanta, GA, 2024.
Xu, J., Becerra B., Ghazarian A., Lyu Y., Schilling J.K., Nasr G., Zargarian E., Fan W., Wong N.D., and Kim J.K. “Devising a Scoring System With Echocardiography in Tamponade Assessment to Guide Pericardiocentesis (E-TAP).” American Society of Echocardiography Scientific Sessions; Seattle, WA, 2022.
Xu, J., Fan, W., Budoff, M.J., Heckbert, S.R., Amsterdam, E.D., Alonso, A., and Wong, N.D. “Intermittent Non-Habitual Coffee Consumption and Risk of Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.” American Heart Association Scientific Sessions; Chicago, IL, 2018.
Godbole, R., Xu, J., Shestakova, A., Youssef, F., Saatian, B. “Rare Variant of High-Grade B-Cell Lymphoma Presenting as a Pleural-Based Mass in an Immunocompetent Patient.” American Thoracic Society International Conference; San Diego, CA, 2018.
Xu, J., Tran, M., Baraghoush, A. “A tangled tale of thrombosis: managing anticoagulation in acute liver and kidney injury.” Society of General Internal Medicine Regional Meeting; Stanford, CA, 2018.
Hines, J., Xu, J. “Emphysematous pyelitis disguised as cholestasis and jaundice.” American College of Physicians Michigan Chapter Annual Scientific Meeting; Sterling Heights, MI, 2016.
Xu, J., Shuman, A.“Soothing and balmy, cure without disfigurement: Benjamin Bye, false promises, and head and neck cancer.” American Academy of Otolaryngology: Head and Neck Surgery Annual Meeting; Orlando, FL, 2014.
Gou, T., Xu, J., Blain-Moraes, S., Mashour, G. “Electroencephalographic power in subjects recovering from deep general anesthesia.” Summer Biomedical Research Program Symposium; Ann Arbor, MI, 2014.
Xu, J., Blain-Moraes, S., Mashour, G. “Directed phase lag index anticipates return of consciousness in subjects recovering from deep general anesthesia.” American Society of Anesthesiologists Annual Meeting; New Orleans, LA, 2014.
Liu, X.S., Chopp, M., Tang, T., Kassis, H., Xu, J., Hozeska-Solgot, A., Zhang, L., Zhang, R.L., and Zhang, Z.G. “The microRNA 17-92 cluster mediates sonic hedgehog-driven neurogenesis in ischemic neural progenitor cells.” International Stroke Conference; New Orleans, LA, 2012.
Publications
Xu, J., Kang J, Schilling J, Paganini-Hill A, Ericson M, Kim, J., Fisher, M. (2025). “Left Atrial Septal Pouch and Risk of Cryptogenic Stroke: A Systematic Review and Meta-Analysis.” Stroke Suppl_1
Xu, J., Haigney, M.C., Levine, B.D., & Dineen, E.H. (2024). “The Tactical Athlete: Definitions, Cardiovascular Assessment, and Management, and "Fit for Duty" Standards.” Cardiol Electrophys Clin, 16(1), 93-105. PMID: 36368814.
Xu, J., Kim, J., Fisher, M. (2024). “The enigma of the left atrial septal pouch.” Trends Cardiovasc Med. doi: 10.1016/j.tcm.2024.01.004.
Digrande, K., Xu, J., Shavelle, D., & Mendoza, F (2024). “Atrial tachycardia facilitating transcatheter edge-to-edge repair for severe functional mitral regurgitation.” JACC Case Reports. doi: 10.1016/j.jaccas.2024.102272
Digrande, K., Xu, J., Dineen, E., Lee, A. (2023). “Isolated double orifice mitral valve in a patient with autosomal dominant polycystic kidney disease.” Cardiovascular Imaging Case Reports. doi: 10.1016/j.case.2023.02.002
Xu, J., Haigney, M., Levine, B., Dineen, E. “The Tactical Athlete: Definitions, assessment, and management of symptoms.” Cardiology Clinics: Sports Cardiology 2022.
Xu, J., Becerra B., Ghazarian A., Lyu Y., Schilling J.K., Nasr G., Zargarian E., Fan W., Wong N.D., and Kim J.K. (2022). “Novel Risk Stratification Scoring System Based on Echocardiography in Tamponade Assessment to Guide Pericardiocentesis (E-TAP).” Journal of the American Society of Echocardiography 35(7).
Xu, J., Patel, P. “Aortic Coarctation.” Ferri’s Clinical Advisor 2022.
Xu, J., Fan, W., Budoff, M.J., Heckbert, S.R., Amsterdam, E.D., Alonso, A., and Wong, N.D. “Intermittent Non-Habitual Coffee Consumption and Risk of Atrial Fibrillation: The Multi-Ethnic Study of Atherosclerosis.” Journal of Atrial Fibrillation, 12(1), 1-6, 2019. PMID 31687073
Xu, J. “Commentary on ‘The Collective Lamentation of the Raggio Tomb.’” Academic Medicine, 94(7), 991, 2019.
Xu, J. “The body vanished: Sebald’s view of dissection in Rembrandt’s ‘The Anatomy Lesson of Dr. Nicolaes Tulp.’” Hektoen International: A Journal of Medical Humanities 6(4), 2014. Available from: http://hekint.org/2017/01/22/the-body-vanished-sebalds-view-of-dissection-in-rembrandts-the-anatomy-lesson-of-dr-nicolaes-tulp/
Xu, J., Shuman, A. “Soothing and balmy, cure without disfigurement”: Benjamin Bye, false promises, and head and neck cancer.” Otolaryngology – Head and Neck Surgery 152(4), 594-597, 2014. PMID 25338669
Xu, J. “I want to tea: an entering medical student’s perspective on geriatrics.” Journal of American Geriatrics Society, 61, 1411, 2013. PMID 23937489
Liu, X.S., Chopp, M., Wang, X.L., Tang, T., Hozeska-Solgot, A., Kassis, H., Zhang, L., Zhang, R.L., Chen, C., Xu, J., and Zhang, Z.G. “MicroRNA-17/92 cluster mediates the proliferation and survival of neural progenitor cells after stroke.” Journal of Biological Chemistry 288(18), 12478-12488, 2013. PMID 23511639
Professional Societies
Diplomate, American Society of Echocardiography
Member, American College of Cardiology
Link to this profile
https://faculty.uci.edu/profile/?facultyId=7181
https://faculty.uci.edu/profile/?facultyId=7181
Last updated
03/15/2025
03/15/2025