Laura Ann Ewell
Assistant Professor, Anatomy & Neurobiology
School of Medicine
School of Medicine
Ph.D., University of Wisconsin, 2010, Physiology
Email: lewell@hs.uci.edu
University of California, Irvine
Irvine, CA 92697
Irvine, CA 92697
Research Interests
memory, epilepsy, place cells, dentate gyrus, hippocampus
Publications
Masala, N., Pofahl M., André N Haubrich, A.N., Islam, K.U.S., Nikbakht, N., Pasdarnavab, M., Kamali, F., Bohmbach, K., Henneberger C., Golcuk, K., Ewell, L.A., Blaess S., Kelly, T., Beck, H., Bioarchive. 2021. Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy. doi: https://doi.org/10.1101/2020.11.23.393694
Pofahl M., Nikbakht N., Haubrich A.N., Nguyen T., Masala N., Braganza O., Macke J.H., Ewell L.A., Golcuk K., Beck H. 2021. Synchronous activity patterns in the Dentate gyrus during immobility. ELife Mar 12;10.
Schweihoff J.F., Loshakov M, Pavlova I, Kück L, Ewell L.A., Schwarz M.K. 2021 DeepLabStream enables closed-loop behavioral experiments using deep learning-based markerless, real-time posture detection. Commun Biol. Jan 29;4(1):130. doi: 10.1038/s42003-021-01654-9.
Ewell, L.A., Fischer K.B., Leibold, C., Leutgeb., S., Leutgeb., J.K., 2019 The impact of pathological high-frequency oscillations on hippocampal network activity in animals with chronic epilepsy. ELife, 22;8, doi: 10.7554/eLife.42148
Madar, A.*, Ewell, L.A.*, Jones M.V., 2019 Pattern separation of spiketrains in hippocampal neurons. Sci. Rep. 9(1):5282; doi: 10.1038/s41598-019-41503-8
Madar, A., Ewell, L.A., Jones M.V., 2019 Temporal pattern separation in hippocampal neurons through multiplexed neural codes. PLoS Comput. Biol. 15(4); doi: 10.1371/journal.pcbi.1006932
Lippi, G., Fernandes, C.C., Ewell, L.A., Romoli, B., Curia G., Taylor S.R., Frady, E.P., Jensen, A.B., Liu J.C., Chaabane, M.M., Belal, C., Nathanson, J.L., Zoli, M., Leutgeb, J.K., Biagini G., Yeo G.W., and Berg, D.K., 2016 MicroRNA – 101 Regulates Multiple Developmental Programs to Constrain Excitation in Adult Neural Networks. Neuron, 92(6):1337-1351
Ewell, L.A., Liang, L., Armstrong, C., Soltesz, I., Leutgeb.,S, Leutgeb., J.K., 2015 Brain state is a major factor in pre-seizure hippocampal network activity and influences success of seizure intervention. J. Neurosci., 35(47): 15635-48
Ewell, L.A., Jones M.V., 2010. Frequency-tuned distribution of inhibition in the dentate gyrus. J. Neurosci. 30(38), 12597-607
Pofahl M., Nikbakht N., Haubrich A.N., Nguyen T., Masala N., Braganza O., Macke J.H., Ewell L.A., Golcuk K., Beck H. 2021. Synchronous activity patterns in the Dentate gyrus during immobility. ELife Mar 12;10.
Schweihoff J.F., Loshakov M, Pavlova I, Kück L, Ewell L.A., Schwarz M.K. 2021 DeepLabStream enables closed-loop behavioral experiments using deep learning-based markerless, real-time posture detection. Commun Biol. Jan 29;4(1):130. doi: 10.1038/s42003-021-01654-9.
Ewell, L.A., Fischer K.B., Leibold, C., Leutgeb., S., Leutgeb., J.K., 2019 The impact of pathological high-frequency oscillations on hippocampal network activity in animals with chronic epilepsy. ELife, 22;8, doi: 10.7554/eLife.42148
Madar, A.*, Ewell, L.A.*, Jones M.V., 2019 Pattern separation of spiketrains in hippocampal neurons. Sci. Rep. 9(1):5282; doi: 10.1038/s41598-019-41503-8
Madar, A., Ewell, L.A., Jones M.V., 2019 Temporal pattern separation in hippocampal neurons through multiplexed neural codes. PLoS Comput. Biol. 15(4); doi: 10.1371/journal.pcbi.1006932
Lippi, G., Fernandes, C.C., Ewell, L.A., Romoli, B., Curia G., Taylor S.R., Frady, E.P., Jensen, A.B., Liu J.C., Chaabane, M.M., Belal, C., Nathanson, J.L., Zoli, M., Leutgeb, J.K., Biagini G., Yeo G.W., and Berg, D.K., 2016 MicroRNA – 101 Regulates Multiple Developmental Programs to Constrain Excitation in Adult Neural Networks. Neuron, 92(6):1337-1351
Ewell, L.A., Liang, L., Armstrong, C., Soltesz, I., Leutgeb.,S, Leutgeb., J.K., 2015 Brain state is a major factor in pre-seizure hippocampal network activity and influences success of seizure intervention. J. Neurosci., 35(47): 15635-48
Ewell, L.A., Jones M.V., 2010. Frequency-tuned distribution of inhibition in the dentate gyrus. J. Neurosci. 30(38), 12597-607
Link to this profile
https://faculty.uci.edu/profile/?facultyId=7043
https://faculty.uci.edu/profile/?facultyId=7043
Last updated
11/08/2021
11/08/2021