Vishal Suresh Chandan

Picture of Vishal Suresh Chandan
Clinical Professor, Pathology
School of Medicine
M.D., University of Bombay, India, 1997
Phone: (714) 456-6141
University of California, Irvine
101 The City Drive South
Orange, CA 92868
Research Interests
Gastrointestinal and Liver Pathology
Awards and Honors
1996: Best graduating medical student for the year. Mahatma Gandhi Missions (M.G.M.) Medical College and Hospitals, University of Bombay, India.

2007: USCAP Abstract Award - Runner up - Rodger Haggit Gastrointestinal Pathology Society.

2017: Hans Popper Hepatopathology Society Trainee Award to Thomas W. Czeczok (Vishal Chandan-Mentor and Senior Author).

2020: John Budd Golden Microscope Teaching Award for the Outstanding Pathology Resident Teacher at University of California, Irvine.
1. Chandan VS, Taylor W. Intraventricular mass in a 6-year-old boy. Arch Pathol Lab Med.2003 May;127:(5):e259-60. PMID:12708929

2. Chandan VS, Wolsh L. Postirradiation angiosarcoma of the prostate. Arch Pathol Lab Med. 2003 Jul; 127(7):876-8. PMID:12823047

3. Nakhla H, Chandan VS, Numann PJ, Landas SK. Pathologic quiz case: a 75-year-old woman with a breast lump. Cystic carcinoma of the breast. Arch Pathol Lab Med. 2003 Dec; 127(12):e436-7. PMID:14632553 DOI:10.1043/1543-2165(2003)1272.0.CO;2

4. Chandan VS, Wang W. Pancreatic heterotopia in the gastric antrum. Arch Pathol Lab Med. 2004 Jan; 128(1):111-2. PMID:14692822

5. Chandan VS, Abraham NZ Jr. A 49-year-old man with left parotid mass. Adenocarcinoma, not otherwise specified. Arch Pathol Lab Med.2004 Apr;128:(4):487-8. PMID:15043479

6. Chandan VS, Wang W, Landas SK. Gastric lipid islands. Arch Pathol Lab Med. 2004 Aug; 128(8):937-8. PMID:15270598

7. Chandan VS, Wilbur D, Faquin WC, Khurana KK. Is c-kit (CD117) immunolocalization in cell block preparations useful in the differentiation of adenoid cystic carcinoma from pleomorphic adenoma? Cancer. 2004 Aug 25; 102(4):207-9. PMID:15368311

8. Chandan VS, Chang J, Schelper RL, Chang HT. A 58-year-old woman presents with paraplegia of three years duration. Neuropathology. 2004 Sep; 24(3):263-265. PMID:15484707

9. Chandan VS, Zimmerman K, Baker P, Scalzetti E, Khurana KK. Usefulness of core roll preparations in immediate assessment of neoplastic lung lesions: comparison to conventional CT scan-guided lung fine-needle aspiration cytology. Chest. 2004 Sep; 126(3):739-43. PMID:15364750

10. Chandan VS, Fung EK, Woods CI, dela Roza G. Primary pleomorphic liposarcoma of the parotid gland: A case report and review of the literature. Am J Otolaryngol. 2004 Nov-Dec; 25(6):432-7. PMID:15547814

11. Pohar S, Taylor W, Chandan VS, Shah H, Sagerman RH. Primary presentation of glioblastoma multiforme with leptomeningeal metastasis in the absence of previous craniotomy. Am J Clin Oncol. 2004 Dec; 27(6):640-1. PMID:15577447

12. Chandan VS, Truong LD, Khurana KK. The utility of B72.3, CEA and Leu M-1 in cell blocks: An adjunct to fine needle aspiration diagnosis of bronchioloalveolar carcinoma of lung. Cancer. 2005 Aug 25; 105(4):246-52. PMID:15971208

13. Chandan VS, Schelper RL, Shrimpton A, Hutchison RE, Chang HT. A 33-year-old man with multiple ring-enhancing lesions in the brain. Neuropathology. 2006 Feb; 26(1):94-7. PMID:16521486

14. Acharya PS, Zukas A, Chandan VS, Katzenstein AL, Puré E. Fibroblast activation protein alpha (FAPa) is expressed in areas of tissue remodeling in Idiopathic Pulmonary Fibrosis. Hum Pathol. 2006 Mar; 37(3):352-60.

15. Chandan VS, Faquin WC, Wilbur DC, Khurana KK. The utility of GLUT-1 immunolocalization in cell blocks: An adjunct to the fine needle aspiration diagnosis of cystic squamous lesions of the head and neck. Cancer. 2006 Apr 25; 108(2):124-8. PMID:16435376 DOI:10.1002/cncr.21714

16. Swartz MF, Lutz CJ, Chandan VS, Landas S, Fink GW. Atrial myxomas: pathologic types, tumor location, and presenting symptoms. J Card Surg. 2006 Jul-Aug; 21(4):435-40. PMID:16846432 DOI:10.1111/j.1540-8191.2006.00265.x

17. Chandan VS, Faquin WC, Wilbur DC, Khurana KK. The role of immunolocalization of CD57 and GLUT-1 in cell blocks in fine-needle aspiration diagnosis of papillary thyroid carcinoma. Cancer. 2006 Oct 25; 108(5):331-6. PMID:16944537 DOI:10.1002/cncr.22172

18. Shah SS, Chandan VS, Wilbur DC, Khurana KK. Glial fibrillary acidic protein and CD57 immunolocalization in cell block preparations is a useful adjunct in the diagnosis of pleomorphic adenoma. Arch Pathol Lab Med. 2007 Sep; 131(9):1373-7. PMID:17824792 DOI:10.1043/1543-2165(2007)131[1373:GFAPAC]2.0.CO;2

19. Haas GP, Delongchamps NB, Jones RF, Chandan V, Serio AM, Vickers AJ, Jumbelic M, Threatte G, Korets R, Lilja H, de la Roza G. Needle biopsies on autopsy prostates: sensitivity of cancer detection based on true prevalence. J Natl Cancer Inst. 2007 Oct 3; 99(19):1484-9. Epub 2007 Sep 25. PMID:17895474 DOI:10.1093/jnci/djm153

20. Delongchamps NB, de la Roza G, Chandan V, Jones R, Sunheimer R, Threatte G, Jumbelic M, Haas GP. Evaluation of prostatitis in autopsied prostates--is chronic inflammation more associated with benign prostatic hyperplasia or cancer? J Urol. 2008 May; 179(5):1736-40. Epub 2008 Mar 17. PMID:18343414 PMCID:2661538 DOI:10.1016/j.juro.2008.01.034

21. Chandan VS, Murray JA, Abraham SC. Esophageal lichen planus. Arch Pathol Lab Med. 2008 Jun; 132(6):1026-9. PMID:18517264 DOI:10.1043/1543-2165(2008)132[1026:ELP]2.0.CO;2

22. Chandan VS, Iacobuzio-Donahue C, Abraham SC. Patchy distribution of pathologic abnormalities in autoimmune pancreatitis: implications for preoperative diagnosis. Am J Surg Pathol. 2008 Dec; 32(12):1762-9. PMID:18779731 DOI:10.1097/PAS.0b013e318181f9ca

23. Delongchamps NB, de la Roza G, Chandan V, Jones R, Threatte G, Jumbelic M, Haas GP. Diagnostic accuracy of extended biopsies for the staging of microfocal prostate cancers in autopsy specimen. Prostate Cancer Prostatic Dis. 2009; 12(2):137-42. Epub 2008 Jul 15. PMID:18626509 PMCID:2680931 DOI:10.1038/pcan.2008.38

24. Leung ST, Chandan VS, Murray JA, Wu TT. Collagenous gastritis: histopathologic features and association with other gastrointestinal diseases. Am J Surg Pathol. 2009 May; 33(5):788-98. PMID:19295410 DOI:10.1097/PAS.0b013e318196a67f

25. Delongchamps NB, Wang CY, Chandan V, Jones RF, Threatte G, Jumbelic M, de la Roza G, Haas GP. Pathological characteristics of prostate cancer in elderly men. J Urol. 2009 Sep; 182(3):927-30. Epub 2009 Jul 17. PMID:19616228 DOI:10.1016/j.juro.2009.05.018

26. Hallemeier CL, Kohli M, Chandan VS, Miller RC, Choo R. Multiple urinary bladder masses from metastatic prostate adenocarcinoma. Rare Tumors. 2010; 2(4):e65. Epub 2010 Dec 31. PMID:21234257 PMCID:3019600 DOI:10.4081/rt.2010.e65

27. Qian Q, Cornell L, Chandan V, Hartman R, Caples S. Hemorrhagic colitis as a presenting feature of Wegener granulomatosis. J Gastrointestin Liver Dis. 2010 Dec; 19(4):445-7. PMID:21188339

28. Smoot RL, Nagorney DM, Chandan VS, Que FG, Schleck CD, Harmsen WS, Kendrick ML. Resection of hepatocellular carcinoma in patients without cirrhosis. Br J Surg. 2011 May; 98(5):697-703. Epub 2011 Jan 31. PMID:21280030 DOI:10.1002/bjs.7401

29. Wang WC, Wu TT, Chandan VS, Lohse CM, Zhang L. Ki-67 and ProExC are useful immunohistochemical markers in esophageal squamous intraepithelial neoplasia. Hum Pathol. 2011 Oct; 42(10):1430-7. Epub 2011 Mar 21. PMID:21420715 DOI:10.1016/j.humpath.2010.12.009

30. Kloesel B, Chandan VS, Alexander GL. An unusual referral for epigastric pain, nausea, abdominal bloating, diarrhea, and weight loss. Gastroenterology. 2012 Dec; 143(6):1439, 1693-3. Epub 2012 Oct 15. PMID:23078989 DOI:10.1053/j.gastro.2012.07.007

31. Neis B, Hart P, Chandan VS, Kane S. Mucosal schwann cell hamartoma of the colon in a patient with ulcerative colitis. Gastroenterol Hepatol (N Y).2013 Mar;9:(3):183-185.

32. * Schoolmeester JK, Jenkins SM, Murray JA, Wu TT, Chandan VS. Increased immunoglobulin G4-positive plasma cells in collagenous sprue. Hum Pathol. 2013 Aug; 44(8):1624-9. Epub 2013 Apr 06. PMID:23566409 DOI:10.1016/j.humpath.2013.01.013

33. Sweetser S, Chandan VS, Baron TH. Dysphagia in Lynch syndrome. Gastroenterology. 2013 Nov; 145(5):945, 1167-8. Epub 2013 Sep 25. PMID:24075947 DOI:10.1053/j.gastro.2013.08.006

34. Sharma A, Freese DK, Chandan V, Zarroug AE, Swain JM, Kumar S. Hepatic cirrhosis secondary to nonalcoholic fatty liver disease in a 12-year-old girl with morbid obesity. Clin Pediatr (Phila). 2014 Jan; 53(1):86-8. Epub 2013 Apr 5 PMID:23564302 DOI:10.1177/0009922813483171

35. Chang K, Sio TT, Chandan VS, Iott MJ, Hallemeier CL. Angiosarcoma of the seminal vesicle: a case report of long-term survival following multimodality therapy. Rare Tumors. 2014 Jan 23; 6(1):5202. Epub 2014 Jan 29. PMID:24711908 PMCID:3977171 DOI:10.4081/rt.2014.5202

36. Mereuta OM, Theis JD, Vrana JA, Law ME, Grogg KL, Dasari S, Chandan VS, Wu TT, Jimenez-Zepeda VH, Fonseca R, Dispenzieri A, Kurtin PJ, Dogan A. Leukocyte cell-derived chemotaxin 2 (LECT2)-associated amyloidosis is a frequent cause of hepatic amyloidosis in the United States. Blood. 2014 Mar 6; 123(10):1479-82. Epub 2014 Jan 10 PMID:24415538 DOI:10.1182/blood-2013-07-517938

37. Venkatesh SK, Chandan V, Roberts LR. Liver masses: a clinical, radiologic, and pathologic perspective. Clin Gastroenterol Hepatol 2014 Sep; 12 (9):1414-29 Epub 2013 Sept 18 PMID:24055987 PMCID:3959647 DOI:10.1016/j.cgh.2013.09.017

38. Chandan VS, Shah SS, Lam-Himlin DM, Petris GD, Mereuta OM, Dogan A, Torbenson MS, Wu TT. Globular hepatic amyloid is highly sensitive and specific for LECT2 amyloidosis. Am J Surg Pathol. 2015 Apr; 39(4):558-64. PMID:25602789 DOI:10.1097/PAS.0000000000000373

39. Wells ML, Venkatesh SK, Chandan VS, Fidler JL, Fletcher JG, Johnson GB, Hough DM, Roberts LR. Biphenotypic hepatic tumors: imaging findings and review of literature. Abdom Imaging 2015 Oct; 40 (7):2293-305 PMID:25952572 DOI:10.1007/s00261-015-0433-9

40. * Liu L, Shah SS, Naini BV, French S, Wu TT, Torbenson MS, Chandan VS. Immunostains Used to Subtype Hepatic Adenomas Do Not Distinguish Hepatic Adenomas From Hepatocellular Carcinomas. Am J Surg Pathol 2016 Aug; 40 (8):1062-9 PMID:26927891
41. Chandan VS, Shah SS, Torbenson MS, Wu TT. Arginase-1 is frequently positive in hepatoid adenocarcinomas. Hum Pathol 2016 Sep; 55:11-6 Epub 2016 Apr 30 PMID:27137985 DOI:10.1016/j.humpath.2016.04.008

42. Shah SS, Chandan VS. Hepatocyte Antigen Expression in Barrett Esophagus and Associated Neoplasia. Appl Immunohistochem Mol Morphol. 2017 Feb 9. doi: 10.1097/PAI.0000000000000491.PMID: 28187035

43. Thompson SM, Wang J, Chandan VS, Glaser KJ, Roberts LR, Ehman RL, Venkatesh SK. MR elastography of hepatocellular carcinoma: Correlation of tumor stiffness with histopathology features-Preliminary findings. Magn Reson Imaging. 2017 Apr;37:41-45. PMID:27845245 DOI:10.1016/j.mri.2016.11.005

44. Mahadev S, Murray JA, Wu TT, Chandan VS, Torbenson MS, Kelly CP, Maki M, Green PH, Adelman D, Lebwohl B. Factors associated with villus atrophy in symptomatic coeliac disease patients on a gluten-free diet. Aliment Pharmacol Ther. 2017 Apr;45(8):1084-1093. doi: 10.1111/apt.13988. PMID: 28220520

45. Shah SS, Wu TT, Torbenson MS, Chandan VS. Aberrant CDX2 expression in Hepatocellular Carcinomas: An Important Diagnostic Pitfall. Hum Pathol. 2017 Jun;64:13-18. doi: 10.1016/j.humpath.2016.12.029. PMID: 28089540

46. Lee HE, Chandan VS, Lee CT, Wu TT. Squamoid Morules in the Pseudoinvasive Foci of Colonic Polyp Morphologically Mimic Invasive Carcinoma. Hum Pathol. 2017 Oct;68:54-60. doi: 10.1016/j.humpath.2017.08.019. Epub 2017 Aug 30.PMID: 28855108

47. Clark I, Shah SS, Moreira R, Graham RP, Wu TT, Torbenson MS, Chandan VS. A Subset of Well Differentiated Hepatocellular Carcinomas are Arginase-1 Negative. Hum Pathol. 2017 Nov;69:90-95. doi: 10.1016/j.humpath.2017.09.007. Epub 2017 Sep 29. PMID: 28970136

48. Chandan VS, Shah SS, Mounajjed T, Torbenson MS, Wu TT. Copper deposition in focal nodular hyperplasia and inflammatory hepatocellular adenoma. J Clin Pathol. 2018 Jun;71(6):504-507. PMID: 29127141

49. Lee HE, Wu TT, Chandan VS, Torbenson MS, Mounajjed T. Colonic Adenomatous Polyps Involving Submucosal Lymphoglandular Complexes: A Diagnostic Pitfall. Am J Surg Pathol. 2018 Aug;42(8):1083-1089. PMID: 29738362

50. Timothy LD, Lehrke HD, Chandan VS, Kolbe AB, Furuya KN. Diffuse Adenomatosis and Hepatocellular Carcinoma Treated with Liver Transplantation in an Adolescent Female with Kabuki Syndrome with a Novel KMT2D Gene Mutation. Case Rep Pediatr. 2019 Apr 24. doi:10.1155/2019/7983824 PMID: 31179148

51. Nasir A, Lehrke HD, Mounajjed T, Said S, Zhang L1, Yasir S, Shah SS, Chandan VS, Smyrk TC, Moreira RK, Boland Froemming JM, Herrera Hernandez LP, Wu TT, Graham RP. Albumin In Situ Hybridization Can Be Positive in Adenocarcinomas and Other Tumors From Diverse Sites. Am J Clin Pathol. 2019 Aug;152(2):190-199. PMID: 31107526

52. Chandan VS, Wu TT. Eosinophilic Esophagitis. American Journal of Surgical Pathology: Reviews and Reports. 2019. Jul-Aug;24(4):144-149.

53. Yuan L, Wu TT, Chandan V, Huang Y, Zhang L. Clinicopathological significance of lymphocytic colitis/collagenous colitis in inflammatory bowel disease [published online ahead of print, 2019 Nov 4]. Hum Pathol. 2019;S0046-8177(19)30193-5. doi:10.1016/j.humpath.2019.09.014 PMID: 31698005

54. Tarabay J, Li X, Chandan VS. Adenosquamous Carcinoma of the Pancreas [published online ahead of print]. Clin Res Hepatol Gastroenterol 2020 Feb 24. PMID: 32107164

55. Hashimoto R, Lee DP, Samarasena JB, Chandan VS, Guo W, Lee JG, Chang KJ. Comparison of Two Specialized Histology Needles for Endoscopic Ultrasound (EUS)-Guided Liver Biopsy: A Pilot Study. Dig Dis Sci. 2020 Jun 17. Online ahead of print. PMID: 32556821

56. Lee W, Li X, Lee S, Chandan VS. Primary pancreatic gastrointestinal stromal tumor. Hepatobiliary Pancreat Dis Int. 2020 Aug 17;S1499-3872(20)30168-5. Online ahead of print. PMID: 32878724

57. Lee HE, Torbenson MS, Wu TT, Chandan VS. Aberrant Keratin Expression Is Common in Primary Hepatic Malignant Vascular Tumors: A Potential Diagnostic Pitfall. Ann Diagn Pathol. 2020 Dec;49:151589. PMID: 32947230

58. Lee W, Li X, Chandan VS. Hepatocellular Carcinomas can be SATB2 positive: An Important Diagnostic Pitfall. Hum Pathol. 2020 Nov;105:47-52. PMID: 32946879

59. Guo W, Lee W, Lu Y, Li X, Chandan VS. Incidence and Significance of GATA3 Positivity in Gallbladder Adenocarcinoma. Hum Pathol. 2020 Dec;106:39-44. PMID: 32991930

60. Lee W, Chandan VS, Johnson C, Li X. Atypical Cells in Peritoneal Cleft: A Pitfall in Diagnosis of Colorectal Adenocarcinoma. Int J Surg Pathol. 2021 Jan 16. Epub ahead of print. PMID: 33455512.
1. Surgical Pathology of Liver Tumors. Mounajjed T, Chandan VS, Torbenson MS. Springer, 2015

2. Surgical Pathology of Non-Neoplastic Gastrointestinal Diseases. Zhang L, Chandan VS, Wu TT. Springer, 2019
1. Chandan VS. Cholangiocarcinoma Precancerous Lesions. In: Mounajjed T, Chandan VS, Torbenson MS. Surgical Pathology of Liver Tumors. Springer, 2015

2. Chandan VS. Metastatic Tumors. In: Mounajjed T, Chandan VS, Torbenson MS. Surgical Pathology of Liver Tumors. Springer, 2015

3. Mounajjed T, Chandan VS. Pseudotumors. In: Mounajjed T, Chandan VS, Torbenson MS. Surgical Pathology of Liver Tumors. Springer, 2015

4. Chandan VS, Wu TT. Granulomatous liver disease In: Moreira R, Zhang L, Torbenson MS. Surgical Pathology of the Liver. Lipincott Williams & Wilkins, 2017

5. Chandan VS, Torbenson MS. Iron overload disease In: Moreira R, Zhang L, Torbenson MS. Surgical Pathology of the Liver. Lipincott Williams & Wilkins, 2017

6. Chandan VS. Normal histology of GI tract. In: Zhang L, Chandan VS, Wu TT. Surgical Pathology of Non-Neoplastic Gastrointestinal Diseases. Springer, 2019

7. Chandan VS. Drugs-induced injury, infections, vascular, congenital, and miscellaneous disorders of the stomach. In: Zhang L, Chandan VS, Wu TT. Surgical Pathology of Non-Neoplastic Gastrointestinal Diseases. Springer, 2019

8. Chandan VS, Wu TT. Drugs-induced injury, infections, vascular, congenital, and miscellaneous disorders of the duodenum. In: Zhang L, Chandan VS, Wu TT. Surgical Pathology of Non-Neoplastic Gastrointestinal Diseases. Springer, 2019

9. Chandan VS. Drugs-induced injury, infections, vascular, congenital, and miscellaneous disorders of the colon. In: Zhang L, Chandan VS, Wu TT. Surgical Pathology of Non-Neoplastic Gastrointestinal Diseases. Springer, 2019

10. Wells M, Chandan VS, Mody K. Biphenotypic Tumors. In. Roberts LR, Yang JD, Venkatesh SK. Evaluation and Management of Liver Masses. Spinger, 2019

1. Chandan VS, Shroff CP. Cytologic grading at fine needle aspiration of breast cancer with comparison of corresponding histologic grading and its possible utility in prognostication and breast cancer patient care. (Dissertation). University of Bombay. 2001.

2. Chandan VS, Shah SS, Torbenson MS, Wu TT. Co-expression of CDX2 and CK20 in hepatocellular carcinoma, an exceedingly rare co-incidence with potential diagnostic pitfall-reply.
Reply to the letter to the editor. Hum Pathol. 2018 Nov;81:299.
Other Experience
Pathology Residency (AP/CP combined)
Upstate Medical University, State University of New York, Syracuse, NY 2001—2005
Surgical Pathology Fellowship
Upstate Medical University, State University of New York, Syracuse, NY 2005—2006
Gastrointestinal & Hepatobiliary Pathology
Mayo Clinic, Rochester, MN 2006—2007
Last updated