Linda Doan

Picture of Linda Doan
Assistant Professor, Dermatology
School of Medicine
Assistant Professor, Pathology
School of Medicine
Co-Director of Dermatopathology, Dermatology
School of Medicine
M.D., University of California, Irvine, 2013
Phone: (949) 824-0606
University of California, Irvine
118 Med Surge 1, Irvine, CA 92697-2400
Mail Code: 2400
Irvine, CA 92697
Research Interests
Dermatopathology, Algorithm in the Assessment of Melanocytic Lesions on Histology, Utility of digital pathology for Mohs histology
Awards and Honors
Graduation Honors, Distinction in research, UC Irvine School of Medicine 2013
Travel Award, Complex Systems Summer School, Santa Fe Institute in Beijing 2008
Graduation honors, Distinction in the Major, Yale University 2002
Sigma Xi Scientific Research Society, Outstanding Scientific Presentation 2006
Book Chapters:
1. Textbook chapter: Doan LT, Scharschmidt TC. “Basic Science.”, In: Alikhan A, Hocker TL. Review of Dermatology. 2nd Edition (invited author, 2nd edition due to be released in 2021).

Journal Articles, Peer- Reviewed
1. Brody G, Yale K, Nguyen A, Juahsz M, Doan L, Mesinkovska N. Laterality and Site-Specific Patterns in Lentigo Maligna and Lentigo Maligna Melanoma. Accepted. SKIN The Journal of Cutaneous Medicine.
2. McFadden JR, Syku M, Barney RE, Stevanovic M, Chaudhari AS, O’Hern KJ, Chambers M, Baker CM, LeBlanc RE, Doan L, Tsongalis GL Hughes EG, Sriharan A. A Novel Method to Detect Copy Number Variation in Melanoma: Droplet Digital PCR for Quantitation of CDKN2A Gene, A Proof of Concept Study. Am J Dermatopathol 2023; Published online ahead of print. May 2023. 37130203.
3. Snyder AN, Zhang D, Dreesen SL, Baltimore CA, Lopez-Garcia DR, Akers JY, Metts CL, Madory JE, Chang PD, Doan LT, Elston DM, Valdebran MA, Luo F, Forcucci JA. Histologic screening of malignant melanoma, Spitz, Dermal and Junctional Melanocytic Nevi Using a Deep Learning Model. Am J Dermatopathol 2022; 44(9):650-657. Sep 2022. 35925282.
4. Birmingham SW, Doan LT, Smith J. Grouped cerebriform papules in a child. J Pediatr 2022; 248:29-130. Sep 2022. 35709955.
5. Wang JV, Doan LT, Yang S, Keller M, Saedi N. Five extracurricular things commonly overlooked by dermatology residents. SKINmed. 2022; 20(2):123-125. Apr 2020. 35532764.
6. Sabeti S, Birmingham SW, Urso B, Nguyen MO, Doan LT, Rojek NW. A case of ice-pack dermatosis in a patient with chronic back pain and review of the literature. Int J Dermatol. 2022; Published online ahead of print. 35506198.
7. Shwe S, Dobry AS, Sharma AA, Doan LT, Rojek NW. Stevens-Johnson syndrome/toxic epidermal necrolysis overlap in a pregnant patient. Cutis 2021; 108(6):E20-E22, Dec 2021. 35167798.
8. Lee K, Evans MG, Yang L, Ng S, Khodadoust M, Brown RA, Trum N, Querfeld C, Doan LT, Song J, Zhang H, Wood GS, Wada DA, Shanmugam V, Haun PL, Duncan LM, Guitart J, Weinstock DM, Nardi V, Choi J. Primary Cytotoxic T Cell Lymphomas Harbor Recurrent Targetable Alterations in the JAK-STAT Pathway. Blood. 2021; 138(23):2435-2440. Dec 2021. 34432866.
9. Sy MY, Fromm E, Doan L, Rojek N, Brandt AU. Nicolau syndrome after glatiramer acetate injection in close proximity to administration of SARS-CoV-2 mRNA vaccine. Neural: Neuroimmunol Neuroinflamm. 2021 Nov 10;9(1):e1112. In print Jan 2022. 34759023.
10. Shwe S, Sharma A, Chahal H, Doan LT, Rojek N. Botulinum toxin injections as a treatment for intractable Raynaud’s disease. Cutis 2021; 108(3):E11-E14. Sep 2021. 34826285.
11. Dobry AS, Virgen CA, Hosking A, Doan L, Lee B, Smith J. Cutaneous reactions with enfortumab vedotin: A case series and review of literature. J Am Acad Dermatol Case Reports 2021; 14:7-9. Aug 2021. 34235241.
12. Chow RY, Jeon US, Levee TM, Kaur G, Cedeno DP, Doan LT, Atwood SX. PI3K Promotes Basal Carcinoma Growth Through Kinase-Induced p21 Degradation. Front. Oncol. 2021; 11;668247. doi: 10.3389/fonc.2021.668247. Jun 2021. 34268113.
13. Chow RY, Levee TM, Kaur G, Cedeno DP, Doan LT, Atwood SX. MTOR promotes basal cell carcinoma growth through atypical PKC. Exp Dermatol 2020. 30(3):358-366. Mar2021. 33617094.
14. Juhasz MLW, Doan L, Rojek NW. Cocaine-induced pemphigus vulgaris. J Am Dermatol Case Reports 2021; 9:45-47. Jan 2021. 33644279.
15. Sharma AN, Dobry AS, Doan L, Rojek NW. Growing scalp mass in an untreated man. J Am Acad Dermatol Case Reports 2020 6(9):956-957. Sep 2020. 32984490.
16. Brody G, Yale K, Nguyen A, Doan L, Linden K. A retrospective, cross-sectional study characterizing site specific and laterality patterns of keratoacanthomas. Int J Derm 2021:60(3):e81-e82. Mar 2021. 32686082
17. Gabra MI, Yang Y, Li H, Senapati P, Hanse EA, Li H, Lowman XH, Tran TQ, Zhang L, Doan LT, Xu X, Schones DE, Fruman DA, Kong, M. Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumor growth. Nat Commun 2020:11(1)3326. Jul 2020 32620791
18. Valdebran M, Doan LT, Elston DM. As Reply to comment on: Pattern hair loss. Assessment of inflammation and fibrosis on histologic sections. J Am Acad Dermatol 2020. [published online ahead of print Aug 2020]. 32330630
19. Valdebran M, Mo J, Doan LT, Elston DM. Reply to comment on: Pattern hair loss. Assessment of inflammation and fibrosiso n histologic sections. J Am Acad Dermatol 2020. [published online ahead of print May 2020]. 32416203
20. Sharma A, Foulad D, Doan L, Lee P, Mesinkovska N. Mohs surgery for the treatment of lentigo maligna and lentigo maligna melanoma – a systematic review. J Dermatolog Treat. [published online ahead of print Nov 2019]. 31696746
21. Chang LW, Doan LT, Fields P, Vignali M, Akilov OE. The Utility of T-cell Clonality in Differential Diagnostics of Acute Graft-vs-Host Disease from Drug Hypersensitivity Reaction. J Invest Dermatol 2020; 140(6):1282-1285. Jun 2020. 31805279
22. Valdebran M, Mo J, Elston DM, Doan LT. Pattern Hair Loss: Assessment Of Inflammation And Fibrosis On Histologic Sections. J Am Acad Dermatol 2020; 82(3):757-758. Mar 2020. 31541751
23. Doan L, Pham C, Kraus C, Elsensohn A, Binder S. A Rare Case of Lipomatous Mixed with Follicular Differentiation. Am J Dermatopathol 2020; 42(2):e26-e27. Feb 2020. 31789835
24. Valdebran M, Kowalsk EH, Kneiber D, Li J, Kim J, Doan L, DeFeraudy S, Amber, KT. Epidermal expression of eotaxins and thymic stromal lymphopoietin in eosinophil rich dermatoses. Arch Dermatol Res 2019; 311(9):705-710. Nov 2019. 31350578
25. Kunishige JB, Doan L, Brodland D, Zitelli JA. 9mm surgical margin required for both LM and MIS as diagnosed in real-world community practice. J Am Acad Dermatol 2019; 81(4):e117-e118. Oct 2019. 31233856
26. Shwe, S, Sharma A, Elsensohn AN, Doan L, Smith J. Multicentric reticulohistiocytosis in a patient with thymic carcinoma. J Am Acad Dermatol Case Reports 2019; 5(8):720-722. Aug 2019. 31440567
27. Wang JV, Doan L, Lee JB. Selection criteria of program directors for dermatopathology fellows. Am J Dermatopathol 2019; 41(8):585-586. Aug 2019. 31335411
28. Kunishige JB, Doan L, Brodland D, Zitelli JA. Comparison of Surgical Margins for Lentigo Maligna and Other Melanoma In Situ. J Am Acad Dermatol 2019; 81(1):204-212. Jul 2019. 31014825
29. Doan L, Al-Khafaji A. Zygomycosis-induced rash after liver transplant. Am J Gastroenterol 2017;112(4):533. Apr 2017. 28381837
30. Canavan T, Sidorsky T, Doan LT, Ricardo-Gonzalez RR, Shen G, Rosenblum MD. A case of Wong-type dermatomyositis with concomitant anti-MDA5 features. J Am Acad Dermatol 2014; 70(3):e62-64. Mar 2014. 24528920
31. Doan LT, Javier AL, Furr NM, Nguyen KL, Cho KW, Monuki ES. A Bmp reporter with ultrasensitive characteristics reveals that high Bmp signaling is not required for cortical hem fate. PlosONE 2012; 7(9):e44009. Sep 2012. 22984456
32. Javier AL, Doan LT, Luong M, Reyes de Mochel NS, Sun A, Monuki ES, Cho KW. Bmp indicator mice reveal dynamic regulation of transcriptional response. PlosONE 2012; 7(9):e42566. Sep 2012. 22984405
33. Hu JS, Doan LT, Currle DS, Rheem JY, Schreyer R, Robert B, Monuki ES. Border formation in a morphogen gradient reduced to single dissociated cells. Proc Natl Acad Sci 2008; 105(9):3398-3403. Mar 2008. 18292231
34. Doan L, Monuki ES. Rapid genotyping of mouse tissue using Sigma’s Extract-N-Amp Tissue PCR kit. Journal of Online Visualized Experiments 2008; (11). Jan 2008. 1906658

Journal Articles, Peer-Reviewed (Submitted):
1. Arnold J, Doan LT. Disseminated coccidiomycosis in an immunocompetent patient.
2. Hosking A, Min M, Doan LT. Lobular panniculitis as a sequelae of Monkey Pox infection.
3. Alder B, Doan LT. Bullous fixed drug eruption as a reaction to the Covid mRNA vaccine.

Non-Peer-Reviewed Scientific or Medical Publications In Print or Other Media:
1. Chahal HS, Doan LT. 51-year-old man with a rapidly growing, thickened fingernail (Onychomatricoma). ASDP Interactive Case Study of the Month. Feb 2020.

Journal Articles for Peer Review (Manuscript In Preparation)
1. Lehmer L, Nguyen B, Doan LT/ Metastatic intraductal breast carcinoma to the skin presenting with pagetoid involvement of the epidermis: a case report and review of literature. Draft in editing/revision.
2. Lehmer L, Skupsky H, Doan LT. Neurotropism in Angioimmunoblastic T-Cell Lymphoma: A Case Series. Manuscript in Preparation.
3. Pham C, Skupsky H, Doan LT. Primary melanoma presenting as vitiligo. Manuscript in Preparation.
4. Doong J, Skupsky H, Doan LT. Basal cell carcinoma with panfollicular differentiation. Manuscript in Preparation.
5. Tarabay J, Skupsky H, Doan LT. Penile porocarcinoma. Manuscript in Preparation.
6. Pourang A, Doan LT, Linden KW. Alpha-Beta Subcutaneous Panniculitis like T-Cell Lymphoma with Aggressive Features. Manuscript in Preparation.
7. Sharma A, Dobry A, Doan LT. Clinicopathologic Challenge: What is your Diagnosis? A case of leprosy. Manuscript in Preparation.
Professional Societies
Organizer of Regional Education Series, Women’s Dermatologic Society (2019)
Voting member, Communications Committee, American Society of Dermatopathology (2021-present)
Member, Women’s Dermatologic Society (WDS) (2016-present)
Member, American Society of Dermatopathology (ASDP) (2015; 2019-present)
Member, American Academy of Dermatology (2012-2017)
Other Experience
Director, Gottschalk Clinical Laboratory
Gottschalk Medical Plaza, Irvine, CA 2018—Pres
Director, Yorba Linda Clinical Laboratory
UCI Health, Yorba Linda, Yorba Linda, CA 2018—Pres
Director, UCI Dermatopathology Unit
UCI Medical Center, Irvine, CA 2018—2020
Co-Director, UCI Dermatopathology Unit
UCI Medical Center, Irvine, CA 2020—Pres
Last updated