Assistant Professor, Biological Chemistry
School of Medicine

Systems Genetics, Endocrine Physiology, Metabolism, Cell-Cell Communication

faculty.sites.uci.edu/marcusseldin/

We are interested in dissecting mechanisms of integrative physiology using systems genetics approaches. Specifically, we are focused in leveraging natural variation in mice and humans to dissect modes of interorgan communication. This entails examination of population data for concordant patterns of genetic architecture, clinical traits and intermediary molecular information (eg. transcripts, proteins and/or metabolites). The basic intuition for these approaches assumes that striking links exists between genetic variation and clinical outcomes which can only be understood when analyzed alongside molecular information. We use a combination of bioinformatics, biochemical and physiologic experimental approaches.

All Publications can be found at: https://www.ncbi.nlm.nih.gov/myncbi/1vmxRLrtbENkL/bibliography/public/

Cellular and Molecular Biosciences

Mathematical and Computational Biology

Link to this profile
https://faculty.uci.edu/profile/?facultyId=6624

Last updated
06/03/2021