Luohua Jiang
Professor, Epidemiology and Biostatistics
Joe C. Wen School of Population & Public Health
Joe C. Wen School of Population & Public Health
Ph.D., UCLA, Biostatistics
M.D., Peking University Health Science Center
M.D., Peking University Health Science Center
University of California, Irvine
856 Health Sciences Quad
Mail Code: 3957
Irvine, CA 92697
856 Health Sciences Quad
Mail Code: 3957
Irvine, CA 92697
Research Interests
Multilevel and Longitudinal Data Analysis, Latent Variable Modeling, Chronic Disease Epidemiology and Prevention, Health Disparities Research
Websites
Research Abstract
My primary research interest is to apply and develop appropriate statistical models to decipher complicated and massive data collected to solve challenging public health problems. In particular, I have been working in the field of translating evidence-based diabetes prevention and management interventions into large-scale public health practice among Native Americans and found many challenging and interesting problems while analyzing this type of data. In the past, I have provided statistical leadership and/or consulting to multiple federally funded studies focusing on reducing health disparities by implementing and evaluating community-based chronic disease prevention interventions designed for minority populations. My major research areas focus on conducting multilevel data analysis and latent variable modelling of those intervention projects as well as secondary data analysis of electronic health record data to study chronic disease epidemiology and health care utilization.
Publications
Hayek S, Li Y, Dai J, Milam J, Jiang L. (2025) Cardiometabolic Factors' and Cardiovascular Risk in Young Adult Cancer Survivors: Evidence from Real-World Data. European Journal of Preventive Cardiology. In press.
Video Summary:
https://drive.google.com/file/d/1yS7WNP4BAAI-R_I4m7EeboNupYAlQFez/view
Video Summary:
https://drive.google.com/file/d/1yS7WNP4BAAI-R_I4m7EeboNupYAlQFez/view
Dai J, Chau T, Corrada MM, Manson SM, O'Connell J, Jiang L. (2025) Race and Ethnicity and Comorbidities Among Medicare Beneficiaries With Young-Onset Dementia. JAMA Network Open. 8(8):e2528001.
Colcord KA, Jiang L, Melikyan ZA, Al-Darsani Z, Arnold NJ, Kristinsson HB, Kawas CH, Corrada MM. (2025) Falls in the Oldest Old: Role of Gender, Living Situation, and Assistive Devices. Gerontology. doi: 10.1159/000547067. ;71(9):723-733
Ports K, Dai J,Conniff K, Corrada MM, Manson SM, O’Connell J, and Jiang L. (2025). Machine learning to predict dementia for American Indian and Alaska Native Peoples. Lancet Regional Health – Americas. 43: 101013.
Dai J, Chang J, Choi JM, Bullock A, Manson SM, O'Connell J, Jiang L. (2025) Trends in anti-diabetic medication use, severe hyperglycaemia and severe hypoglycaemia among American Indian and Alaska Native Peoples, 2009-2013 Diabetes, Obesity, and Metabolism. 27(1):328-337..
Li J, Bea JW, LaMonte M, Jiang L, Reding K, Garcia L, Manson JE, Follis S, Odegaard A.O. (2025) Effects of moderate/vigorous activity on 3-year body composition changes in postmenopausal women: a target trial emulation. American Journal of Epidemiology. 194(4):1032-1042.
Brega, AG, Stotz SA, Moore KR, McNulty MC, Jiang, L. (2025) Reliability and Validity of Diabetes Nutrition Self-Efficacy and Behavior Measures for the "What Can I Eat" Diabetes Nutrition Education Program for American Indian and Alaska Native Adults With Type 2 Diabetes. Journal of the Academy of Nutrition and Dietetics. 125(1):78-89.e1.
Melikyan ZA, Kawas C, Paganini-Hill A, Jiang L, Bukhari S, Montine TJ, Mander BA, Corrada MM. (2024) Neuropathologic changes at age 90+ related to sleep duration 19 to 40 years earlier: The 90+ Study. Alzheimers & Dementia. 20(5):3495-3503.
Zhu Y, Shi Y, Bartell SM, Corrada MM, Manson SM, O'Connell J, Jiang L. (2024) Potential Effects of Long-Term Exposure to Air Pollution on Dementia: A Longitudinal Analysis in American Indians Aged 55 Years and Older. International Journal of Environmental Research and Public Health. 21(2): 128.
Dai J, Niu X, Bullock A, Manson SM, O'Connell J, Jiang L. (2024) Prevalence of Diagnosed Type 1 and Type 2 Diabetes Among American Indian and Alaska Native Peoples in 2012-2013. Diabetes Care. 47(1): e1-e3.
Dai J, Ports KD, Corrada MM, Odegaard AO, O'Connell J, Jiang L. (2022) Metformin and Dementia Risk: A Systematic Review with Respect to Time Related Biases. Journal of Alzheimer’s Disease Report. 6(1): 443-459.
O'Connell, J, Grau, L, Goins, RT, Perraillon, M, Winchester, B, Corrada, MM, Manson, SM, Jiang, L. (2022) The Costs of Treating All-cause Dementia among American Indians and Alaska Native Adults who Access Services through the Indian Health Service and Tribal Health Programs. Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association. 18(11): 2055-2066.
Banack, HR, Chang, J, Stefanick, ML, Arnold, M, Anton-Culver, H. Jiang, L. § (2022) Relationship between BMI trajectories and cardiometabolic outcomes in postmenopausal women: a growth mixture modeling approach. Annals of Epidemiology, 72: 9-17.
Adamsen, C, Manson, SM. Jiang, L. (2021) The Association of Cultural Participation and Social Engagement with Self-Reported Diagnosis of Memory Problems among American Indian and Alaska Native Elders. Journal of Aging and Health, 33: 60S-67S.
Brega, A.G., Jiang, L., Johnson, R.L., Wilson, A.R., Schmiege S.J., Albino, J. (2020) Health literacy and parental oral health knowledge, beliefs, behavior, and status among parents of American Indian newborns. Journal of Racial and Ethnic Health Disparities, 7(4): 598-608.
Jiang, L., Beals, J., Whitesell, N.R., Roubideaux, Y., Manson, S.M. (2007). Association between Diabetes and Mental disorders in Two American Indian Reservation Communities. Diabetes Care, 30 (9): 2228-2229.
Jiang, L., Beals, J., Whitesell, N.R., Roubideaux, Y., Manson, S.M. (2008). Stress Burden and Diabetes in Two American Indian Reservation Communities. Diabetes Care, 31(3):427-429.
Jiang, L., Beals, J., Whitesell, N.R., Roubideaux, Y., Manson, S.M. (2009). Health Related Quality of Life and Help Seeking among American Indians with Diabetes and Hypertension. Quality of Life Research, 18(6):709-718.
Manson, S.M., Jiang, L., Zhang, L., Beals, J., Acton, K.J., Roubideaux, Y. (2011). The Special Diabetes Program for Indians Healthy Heart Demonstration Project: Retaining American Indians and Alaska Natives in Cardiovascular Risk Reduction. The Gerontologist. 51 (supp 1): S21-S32.
Jiang, L., Beals, J., Zhang, L., Mitchell, C.M., Manson, S.M., Acton, K.J., Roubideaux, Y. (2012) Latent Class Analysis of Stages of Change for Multiple Health Behaviors: Results from the Special Diabetes Program for Indians Diabetes Prevention Demonstration Project. Prevention Science, 13(5):449-61.
Neumann, C.G., Jiang, L., Weiss, R.E., Grillenberger, M., Gewa, C.G., Siekmann, J.H., Murphy, S.P., Bwibo, N.O. (2013) Meat supplementation increases arm muscle area and physical activity in Kenyan School Children. British Journal of Nutrition, 109(7):1230-40.
Jiang, L., Manson, S.M., Beals, J., Henderson, W.G., Huang, H., Acton, K.J., Roubideaux, Y. (2013) Translating the Diabetes Prevention Program into American Indian and Alaska Native Communities: Results from the Special Diabetes Program for Indians Diabetes Prevention Demonstration Project. Diabetes Care, 36(7): 2027-34
Ory, M. G., Ahn, S., Jiang, L., Smith, M. L., Ritter, P., Whitelaw, N., Lorig, K. (2013) Successes of a National Study of the Chronic Disease Self-Management Program: Meeting the Triple Aim of Health Care Reform. Medical Care, 51(11):992-8.
Kaufman, C.E., Croy, C., Jiang, L., Beals, J. (2013) Depression in 2 American Indian Tribes: A Multilevel Analysis. Journal of Consulting and Clinical Psychology, 81(6):1040-51.
Sepah, C.S., Jiang, L., Peters, A.L. (2014) Translating the Diabetes Prevention Program into an Online Social Network: Validation against CDC Standards. Diabetes Educator, 40(4): 435-443.
Moore, K., Jiang, L., Manson, S.M., Beals, J., Henderson, W.G., Pratte, K., Acton, K.J., Roubideaux, Y. (2014) Case Management to Reduce Cardiovascular Disease Risk among American Indians and Alaska Natives with Diabetes: Results from the Special Diabetes Program for Indians Healthy Heart Demonstration Project. American Journal of Public Health, American Journal of Public Health, 104(11):e158-164.
Jiang, L., Manson, S.M., Dill, E., Huang, H., Beals, J., Johnson, A., Acton, K.J., Roubideaux, Y. (2015) Participant and Site Characteristics Related to Participant Retention in a Diabetes Prevention Translational Project. Prevention Science, 16(1): 41-52.
Jiang, L., Huang, H., Johnson, A., Dill, E., Beals, J., Manson, S.M., Roubideaux, Y. (2015) Socioeconomic Disparities in Weight and Behavioral Outcomes among American Indians and Alaska Native Participants of a Lifestyle Intervention Project. Diabetes Care, 38(11):2090-9.
Jiang, L., Chen, S., Zhang, B., Beals, J., Mitchell, C.M., Manson, S.M., Roubideaux, Y. (2016) Longitudinal Patterns of Stages of Change for Exercise and Lifestyle Intervention Outcomes. Prevention Science, 17(3):398-409.
Arnold, M., Jiang, L., Stefanick, M.L., Johnson, K.C., Lane, D.S., Leblanc, E.S., Prentice, R., Rohan, T.E., Snively, B.M., Vitolins, M., Zaslavsky, O., Soerjomataram, I., Anton-Culver, H. (2016) Duration of Adulthood Overweight, Obesity, and Cancer Risk in the Women’s Health Initiative: A Longitudinal Study from the United States. PLOS Medicine, 13(8):e1002081.
Nuyujukian, D.S., Beals, J., Huang, H., Johnson, A., Bullock A., Manson, S.M., Jiang, L. (2016) Sleep Duration and Diabetes Risk in American Indian and Alaska Native Participants of a Lifestyle Intervention Project. Sleep, 39(11):1919-1926.
Jiang, L., Chang, J., Beals, J., Bullock, A., Manson, S.M. (2018) Neighborhood characteristics and lifestyle intervention outcomes: Results from the Special Diabetes Program for Indians. Preventive Medicine, 111: 216-224.
Jiang, L., Johnson, A., Pratte, K., Beals, J., Bullock, A., Manson, S.M. (2018) Long-term outcomes of lifestyle intervention to prevent diabetes in American Indian and Alaska Native communities: the Special Diabetes Program for Indians Diabetes Prevention Program. Diabetes Care, 41: 1462-1470.
Jiang, L., Chen, S., Beals, J., Siddique, J., Hamman, R.F., Bullock, A., Manson, S.M. (2019) Evaluating Community-Based Translational Interventions Using Historical Controls: Propensity Score vs. Disease Risk Score Approach. Prevention Science, 20: 598-608.
Jiang, L., Chang, J., Ziogas, A., Deapen, D., Reynolds, P., Bernstein, L., Anton-Culver, H. (2019) Secondhand smoke, obesity, and risk of type II diabetes among California teachers. Annals of Epidemiology, 32: 35-42.
Nuyujukian, D.S., Beals, J., Huang, H., Johnson, A., Bullock A., Manson, S.M., Jiang, L.(2019) Associations of sleep duration with cardiometabolic outcomes in American Indians and Alaska Natives and other race/ethnicities: results from the BRFSS. Sleep Health, 5: 344-351.
Pratte, K., Johnson, A., Beals, J., Bullock, A., Manson, S.M., Jiang, L. (2019) Regression to Normal Glucose Regulation in American Indians and Alaska Natives of a Diabetes Prevention Program. Diabetes Care, 42: 1209-1216.
Jiang, L., Beals, J., Whitesell, N.R., Roubideaux, Y., Manson, S.M. (2008). Stress Burden and Diabetes in Two American Indian Reservation Communities. Diabetes Care, 31(3):427-429.
Jiang, L., Beals, J., Whitesell, N.R., Roubideaux, Y., Manson, S.M. (2009). Health Related Quality of Life and Help Seeking among American Indians with Diabetes and Hypertension. Quality of Life Research, 18(6):709-718.
Manson, S.M., Jiang, L., Zhang, L., Beals, J., Acton, K.J., Roubideaux, Y. (2011). The Special Diabetes Program for Indians Healthy Heart Demonstration Project: Retaining American Indians and Alaska Natives in Cardiovascular Risk Reduction. The Gerontologist. 51 (supp 1): S21-S32.
Jiang, L., Beals, J., Zhang, L., Mitchell, C.M., Manson, S.M., Acton, K.J., Roubideaux, Y. (2012) Latent Class Analysis of Stages of Change for Multiple Health Behaviors: Results from the Special Diabetes Program for Indians Diabetes Prevention Demonstration Project. Prevention Science, 13(5):449-61.
Neumann, C.G., Jiang, L., Weiss, R.E., Grillenberger, M., Gewa, C.G., Siekmann, J.H., Murphy, S.P., Bwibo, N.O. (2013) Meat supplementation increases arm muscle area and physical activity in Kenyan School Children. British Journal of Nutrition, 109(7):1230-40.
Jiang, L., Manson, S.M., Beals, J., Henderson, W.G., Huang, H., Acton, K.J., Roubideaux, Y. (2013) Translating the Diabetes Prevention Program into American Indian and Alaska Native Communities: Results from the Special Diabetes Program for Indians Diabetes Prevention Demonstration Project. Diabetes Care, 36(7): 2027-34
Ory, M. G., Ahn, S., Jiang, L., Smith, M. L., Ritter, P., Whitelaw, N., Lorig, K. (2013) Successes of a National Study of the Chronic Disease Self-Management Program: Meeting the Triple Aim of Health Care Reform. Medical Care, 51(11):992-8.
Kaufman, C.E., Croy, C., Jiang, L., Beals, J. (2013) Depression in 2 American Indian Tribes: A Multilevel Analysis. Journal of Consulting and Clinical Psychology, 81(6):1040-51.
Sepah, C.S., Jiang, L., Peters, A.L. (2014) Translating the Diabetes Prevention Program into an Online Social Network: Validation against CDC Standards. Diabetes Educator, 40(4): 435-443.
Moore, K., Jiang, L., Manson, S.M., Beals, J., Henderson, W.G., Pratte, K., Acton, K.J., Roubideaux, Y. (2014) Case Management to Reduce Cardiovascular Disease Risk among American Indians and Alaska Natives with Diabetes: Results from the Special Diabetes Program for Indians Healthy Heart Demonstration Project. American Journal of Public Health, American Journal of Public Health, 104(11):e158-164.
Jiang, L., Manson, S.M., Dill, E., Huang, H., Beals, J., Johnson, A., Acton, K.J., Roubideaux, Y. (2015) Participant and Site Characteristics Related to Participant Retention in a Diabetes Prevention Translational Project. Prevention Science, 16(1): 41-52.
Jiang, L., Huang, H., Johnson, A., Dill, E., Beals, J., Manson, S.M., Roubideaux, Y. (2015) Socioeconomic Disparities in Weight and Behavioral Outcomes among American Indians and Alaska Native Participants of a Lifestyle Intervention Project. Diabetes Care, 38(11):2090-9.
Jiang, L., Chen, S., Zhang, B., Beals, J., Mitchell, C.M., Manson, S.M., Roubideaux, Y. (2016) Longitudinal Patterns of Stages of Change for Exercise and Lifestyle Intervention Outcomes. Prevention Science, 17(3):398-409.
Arnold, M., Jiang, L., Stefanick, M.L., Johnson, K.C., Lane, D.S., Leblanc, E.S., Prentice, R., Rohan, T.E., Snively, B.M., Vitolins, M., Zaslavsky, O., Soerjomataram, I., Anton-Culver, H. (2016) Duration of Adulthood Overweight, Obesity, and Cancer Risk in the Women’s Health Initiative: A Longitudinal Study from the United States. PLOS Medicine, 13(8):e1002081.
Nuyujukian, D.S., Beals, J., Huang, H., Johnson, A., Bullock A., Manson, S.M., Jiang, L. (2016) Sleep Duration and Diabetes Risk in American Indian and Alaska Native Participants of a Lifestyle Intervention Project. Sleep, 39(11):1919-1926.
Jiang, L., Chang, J., Beals, J., Bullock, A., Manson, S.M. (2018) Neighborhood characteristics and lifestyle intervention outcomes: Results from the Special Diabetes Program for Indians. Preventive Medicine, 111: 216-224.
Jiang, L., Johnson, A., Pratte, K., Beals, J., Bullock, A., Manson, S.M. (2018) Long-term outcomes of lifestyle intervention to prevent diabetes in American Indian and Alaska Native communities: the Special Diabetes Program for Indians Diabetes Prevention Program. Diabetes Care, 41: 1462-1470.
Jiang, L., Chen, S., Beals, J., Siddique, J., Hamman, R.F., Bullock, A., Manson, S.M. (2019) Evaluating Community-Based Translational Interventions Using Historical Controls: Propensity Score vs. Disease Risk Score Approach. Prevention Science, 20: 598-608.
Jiang, L., Chang, J., Ziogas, A., Deapen, D., Reynolds, P., Bernstein, L., Anton-Culver, H. (2019) Secondhand smoke, obesity, and risk of type II diabetes among California teachers. Annals of Epidemiology, 32: 35-42.
Nuyujukian, D.S., Beals, J., Huang, H., Johnson, A., Bullock A., Manson, S.M., Jiang, L.(2019) Associations of sleep duration with cardiometabolic outcomes in American Indians and Alaska Natives and other race/ethnicities: results from the BRFSS. Sleep Health, 5: 344-351.
Pratte, K., Johnson, A., Beals, J., Bullock, A., Manson, S.M., Jiang, L. (2019) Regression to Normal Glucose Regulation in American Indians and Alaska Natives of a Diabetes Prevention Program. Diabetes Care, 42: 1209-1216.
Grants
R01AG061189, NIA, 2019-2026, "Dementia Epidemiology, Health service Utilization and Treatment Costs among American Indian and Alaska Native Elders", Role: Co-PI.
R21DK108187, NIDDK, 2016-2019, “Comparative Effectiveness Evaluation of a Diabetes Case Management Intervention in AI/AN Communities”, Role: PI.
HHS1236201000002C, Indian Health Service, 2013 - 2019, “Special Diabetes Program for Indians Demonstration Projects Coordinating Center", Role: PI of UCI subcontract
ADA #7-12-CT-36, American Diabetes Association, 2012-2016, "Multilevel analysis of the translational effects of lifestyle intervention among AI/ANs", Role: PI.
P30DK092923, NIDDK, 2012-2021, "Center for American Indian and Alaska Native Diabetes Translational Research", Role: UCI Subcontract PI.
U54MD000507, NIMHD, 2017-2022, "Center for American Indian and Alaska Health Disparities", Role: UCI Subcontract PI.
CDPH #24-10131 Jiang (PI) 07/01/24 – 06/30/28
The epidemiology, risk prediction, and health care utilization for Alzheimer’s disease and related dementias among California American Indian and Alaska Native Medicare Beneficiaries
Research Centers
https://sites.uci.edu/cardiometabolic/
Link to this profile
https://faculty.uci.edu/profile/?facultyId=6109
https://faculty.uci.edu/profile/?facultyId=6109
Last updated
10/18/2025
10/18/2025